SCHEMBL10929488

SCHEMBL10929488

O=[N+]([O-])c1ccc(P(O)(O)=S)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.50
CA2 P00918 3/20 0.50
CES1 P23141 2/20 0.50
CES2 O00748 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 2/20 0.46
ACHE P22303 1/20 0.46
MAPK1 P28482 2/20 0.46
LMNA P02545 2/20 0.46
AKR1C3 P42330 1/20 0.46
CA12 O43570 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP14 P50281 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
THRB P10828 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11660222 0.83 ALDH1A1 (0.48) CA1CA2CES1CES2TDP1
SCHEMBL23270417 0.80 CA1 (0.57) CA1CA2CES1CES2TDP1
SCHEMBL356640 0.80 CA2 (0.57) CA1CA2CES1CES2TDP1
Phosphoric Acid SCHEMBL28639141 0.79 CA1 (0.65) CA1CA2CES1CES2TDP1
SCHEMBL28268315 0.78 CA2 (0.55) CA1CA2CES1CES2TDP1
Nitrobenzene SCHEMBL28339777 0.76 ALDH1A1 (0.73) CA1CA2CES1CES2TDP1
Hydrogen Peroxide SCHEMBL28789390 0.75 ALDH1A1 (0.72) CA1CA2CES1CES2TDP1
SCHEMBL27752664 0.75 ALDH1A1 (0.65) CA1CA2CES1TDP1ALDH1A1
SCHEMBL22567 0.75 ALDH1A1 (0.72) CA1CA2CES1TDP1ALDH1A1
SCHEMBL27909482 0.75 ALDH1A1 (0.72) CA1CA2CES1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4548931-A Thiophosphonic acid ester pesticides BAYER AKTIENGESELLSCHAFT (DE) 1985-10-22 US disclosed