SCHEMBL356640

SCHEMBL356640

O=[N+]([O-])c1ccc(P(=O)(O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.57
CA1 P00915 4/20 0.57
CES1 P23141 2/20 0.57
CES2 O00748 1/20 0.57
CA12 O43570 2/20 0.52
MMP2 P08253 2/20 0.52
AKR1C3 P42330 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP14 P50281 1/20 0.52
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.48
ACHE P22303 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28268315 0.98 CA2 (0.55) CA2CA1CES1CES2CA12
SCHEMBL23270417 0.86 CA1 (0.57) CA2CA1CES1CES2CA12
Phosphoric Acid SCHEMBL28639141 0.85 CA1 (0.65) CA2CA1CES1CES2CA12
Phenylphosphonic Acid SCHEMBL28269525 0.85 ALDH1A1 (0.64) CA2CA1CES1CES2CA12
Diethanolamine SCHEMBL28185293 0.84 TSHR (0.46) CA2CA1CES1CES2CA12
SCHEMBL7922647 0.82 KMT2A (0.68) MMP9ALDH1A1MAPK1
SCHEMBL10976942 0.81 ALDH1A1 (0.52) CA2CA1CES1CES2CA12
SCHEMBL10929488 0.80 CA1 (0.50) CA2CA1CES1CES2CA12
Methyl Alcohol SCHEMBL27456236 0.80 HSD17B10 (0.70) CA2CA1CES1CA12TDP1
SCHEMBL31684238 0.79 ALDH1A1 (0.56) CA2CA1CES1CES2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100120044-A1 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS QIAGEN GMBH (DE) 2010-05-13 US claimed
EP-2142671-A2 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS Qiagen GmbH (DE) 2010-01-13 EP claimed
WO-2008119539-A2 MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS QIAGEN GMBH (DE) 2008-10-09 WO claimed
EP-1196631-B1 Modifications of ribonucleic acids CYCLOPS GENOME SCIENCES LTD (GB) 2006-12-06 EP claimed
EP-1601468-A4 SURFACE-BONDED, ORGANIC ACID-BASED MONO-LAYERS UNIV PRINCETON (US) 2006-11-29 EP claimed
US-20050272679-A1 Modified polynucleotides and uses thereof CYCLOPS GENOME SCIENCES LIMITED (GB) 2005-12-08 US claimed
EP-1601468-A2 SURFACE-BONDED, ORGANIC ACID-BASED MONO-LAYERS PRINCETON UNIVERSITY (US) 2005-12-07 EP claimed
US-20040265571-A1 Surface-bonded, organic acid-based mono-layers PRINCETON UNIVERSITY (US) 2004-12-30 US claimed
WO-2004072120-A2 SURFACE-BONDED, ORGANIC ACID-BASED MONO-LAYERS PRINCETON UNIVERSITY (US) 2004-08-26 WO claimed
US-20030039985-A1 Modified polynucleotides and uses thereof CYCLOPS GENOME SCIENCES LIMITED (GB) 2003-02-27 US claimed
EP-1019419-A4 PHOSPHONATED AGENTS AND THEIR ANTIANGIOGENIC AND ANTITUMORIGENIC USE UNIV KENTUCKY RES FOUND (US) 2001-12-12 EP claimed
WO-2000066605-A2 POLYNUCLEOTIDES CYCLOPS GENOME SCIENCES LIMITED (GB) 2000-11-09 WO claimed
EP-1019419-A1 PHOSPHONATED AGENTS AND THEIR ANTIANGIOGENIC AND ANTITUMORIGENIC USE The University of Kentucky Research Foundation (US) 2000-07-19 EP claimed
WO-1999005148-A1 PHOSPHONATED AGENTS AND THEIR ANTIANGIOGENIC AND ANTITUMORIGENIC USE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1999-02-04 WO claimed
US-5633111-A Photoresist composition and article containing 1,2-quinonediazide and an organic phosphorous acid compound FUJI PHOTO FILM CO., LTD. (JP) 1997-05-27 US claimed
US-5254430-A Lithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1993-10-19 US claimed
CN-122074095-A Catalyst and method for hydrogen production by proton reduction 瑞内尔公司 2026-05-22 CN disclosed
US-12565666-B2 Methods and compositions for modulating a genome FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2026-03-03 US disclosed
US-4421516-A Process for preparing discharge resist prints on hydrophobic textile materials CASSELLA AKTIENGESELLSCHAFT (DE) 1983-12-20 US disclosed
EP-0088996-A1 Process for the production of discharge resist prints on hydrophobic textile materials CASSELLA Aktiengesellschaft (DE) 1983-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565666-B2 Methods and compositions for modulating a genome RPRD2, ERN2, TPR CA2 4859/4885CA1 4593/4885CES1 3384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.