SCHEMBL4654756

SCHEMBL4654756

CCCCCCCCCCCCCCCCCC(=O)OC1(O)CC[C@@]2(C)C(=CCC3C2CC[C@@]2(C)C3CC[C@@H]2[C@H](C)CCCC(C)C)C1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.59
CYP46A1 Q9Y6A2 2/20 0.58
LMNA P02545 1/20 0.58
ABCB1 P08183 1/20 0.58
OSBP P22059 1/20 0.58
RORC P51449 1/20 0.58
OSBP2 Q969R2 1/20 0.58
POLA1 P09884 1/20 0.58
GRIN1 Q05586 14/20 0.56
GRIN2B Q13224 14/20 0.56
GRIN2A Q12879 12/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27318 0.89 CYP46A1 (0.56) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL10929500 0.88 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL10929495 0.88 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL10930823 0.88 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL7741660 0.85 USP2 (0.70) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL4284415 0.84 USP2 (0.69) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18310374 0.84 POLA1 (0.70) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL4624683 0.84 POLA1 (0.70) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL126915 0.84 POLA1 (0.70) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL1667802 0.84 POLA1 (0.70) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602354-B1 Use of polyglutamic acid or its salts MEIJI SEIKA KAISHA (JP) 2008-11-05 EP disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 US disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC USP2 3069/4885CYP46A1 3388/4885LMNA 2112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.