Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL4159325 | 0.84 | — | — | |
| Beta-Alanine SCHEMBL27659816 | 0.80 | — | — | |
| Glycine SCHEMBL93765 | 0.79 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL3640989 | 0.79 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL13169653 | 0.79 | — | — | |
| Glycine SCHEMBL2116443 | 0.79 | — | — | |
| Glycine SCHEMBL6675874 | 0.79 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL391786 | 0.79 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL391027 | 0.79 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL6163 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548760-A | Process for preparing phosphonomethylated amino acids | STAUFFER CHEMICAL COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| US-4491548-A | Process for preparing phosphonomethylated amino acids | STAUFFER CHEMICAL COMPANY (US) | 1985-01-01 | — | — | US | disclosed |