Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14054235 | 0.83 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL347390 | 0.82 | MAPT (0.59) | IMPDH2IMPDH1ALDH1A1GAAMAPT | |
| SCHEMBL30839714 | 0.82 | MAPT (0.59) | IMPDH2IMPDH1ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL10604756 | 0.80 | MAPT (0.57) | IMPDH2IMPDH1ALDH1A1GAAMAPT | |
| SCHEMBL7632963 | 0.79 | IMPDH2 (0.46) | HSP90AA1HSP90AB1IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL20692608 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EHTR2BAGPAT2RECQL | |
| SCHEMBL16093812 | 0.78 | GAA (0.52) | HSP90AA1HSP90AB1ALDH1A1GAAKDM4E | |
| SCHEMBL110433 | 0.78 | MAPT (0.55) | IMPDH2IMPDH1ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL1143381 | 0.76 | MAPT (0.53) | ALDH1A1GAAMAPTKDM4ETSHR | |
| SCHEMBL7897905 | 0.75 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153954-A1 | INSECTICIDAL SUBSTITUTED BIPHENYL BENZOYLUREAS | FMC Corporation (US) | 1985-09-11 | — | — | EP | disclosed |
| WO-1985001047-A1 | INSECTICIDAL SUBSTITUTED BIPHENYL BENZOYLUREAS | FMC CORPORATION (US) | 1985-03-14 | — | — | WO | disclosed |