Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 4/20 | 0.57 |
| ▸ | IMPDH2 known ✓ | P12268 | 1/20 | 0.56 |
| ▸ | IMPDH1 known ✓ | P20839 | 1/20 | 0.56 |
| ▸ | CYP19A1 known ✓ | P11511 | 4/20 | 0.42 |
| ▸ | LCK known ✓ | P06239 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347390 | 0.98 | MAPT (0.59) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL30839714 | 0.98 | MAPT (0.59) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL30839803 | 0.89 | MAPT (0.52) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL27185970 | 0.89 | MAPT (0.52) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL6011530 | 0.89 | MAPT (0.52) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL311721 | 0.86 | MAPT (0.53) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL29764084 | 0.86 | MAPT (0.53) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL29287691 | 0.86 | KIT (0.52) | MAPTGAAMAPK1HTTTSHR | |
| SCHEMBL3791216 | 0.85 | MAPT (0.52) | MAPTGAAMAPK1HTTTSHR | |
| Hydrochloric Acid SCHEMBL2097510 | 0.84 | CYP1A1 (0.49) | MAPTGAAMAPK1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4684025-A1 | RECOMBINANT AAV FOR THE GENE THERAPY OF WILSON DISEASE | Skyline Therapeutics Limited (KY) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024193638-A9 | RECOMBINANT AAV FOR THE GENE THERAPY OF WILSON DISEASE | SKYLINE THERAPEUTICS (SHANGHAI) CO., LTD. (CN) | 2025-04-03 | — | — | WO | disclosed |
| WO-2024193638-A1 | RECOMBINANT AAV FOR THE GENE THERAPY OF WILSON DISEASE | SKYLINE THERAPEUTICS (SHANGHAI) CO., LTD. (CN) | 2024-09-26 | — | — | WO | disclosed |
| WO-2020203818-A1 | ASBESTOS DETECTING AGENT, ASBESTOS DETECTING KIT, AND ASBESTOS DETECTING METHOD | 広島県 | 2020-10-08 | — | — | WO | disclosed |
| EP-0176357-B1 | ANALYTICAL ELEMENT AND METHOD FOR COLORIMETRIC DETERMINATION OF TOTAL CHOLESTEROL | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-06-07 | — | — | EP | disclosed |
| US-4680259-A | Analytical element and method for colorimetric determination of total cholesterol | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0176357-A1 | Analytical element and method for colorimetric determination of total cholesterol | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-04-02 | — | — | EP | disclosed |
| EP-0076024-B1 | FLUIDISING AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-09-18 | — | — | EP | disclosed |
| US-4461647-A | NONAQUEOUS DISPERSION OF PIGMENTS AND DISAZO FLOW CONTROL AGENT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1984-07-24 | — | — | US | disclosed |
| US-RE29725-E | Analytical test pack and process for analysis | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-08-08 | — | — | US | disclosed |