Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924406 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL2235673 | 0.91 | NPY1R (0.37) | GAADRD2DRD4HRH2HRH1 | |
| SCHEMBL26629591 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL164608 | 0.86 | TSHR (0.41) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL1531822 | 0.84 | KMT2A (0.41) | GAATSHRL3MBTL1HPGDMEN1 | |
| SCHEMBL25836761 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL3924367 | 0.82 | TSHR (0.37) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL12424625 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL10049967 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KDM4EGAATSHRL3MBTL1 | |
| SCHEMBL1816802 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545095-B1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES, NON-AQUEOUS DISPERSIONS THEREOF AND ARTICLES PREPARED THEREWITH | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-1776436-B1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2019-05-08 | — | — | EP | disclosed |
| EP-2545140-B1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES | TRANSITIONS OPTICAL INC (US) | 2017-06-21 | — | — | EP | disclosed |
| US-8563212-B2 | Methods for producing photosensitive microparticles, non-aqueous dispersions thereof and articles prepared therewith | TRANSITIONS OPTICAL, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-8563213-B2 | Methods for producing photosensitive microparticles | TRANSITIONS OPTICAL, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| EP-2545095-A1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES, NON-AQUEOUS DISPERSIONS THEREOF AND ARTICLES PREPARED THEREWITH | Transitions Optical, Inc. (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-2545140-A1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES | Transitions Optical, Inc. (US) | 2013-01-16 | — | — | EP | disclosed |
| US-8153344-B2 | Methods for producing photosensitive microparticles, aqueous compositions thereof and articles prepared therewith | PPG INDUSTRIES OHIO, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| EP-1778815-B1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES, AQUEOUS COMPOSITIONS THEREOF AND ARTICLES PREPARED THEREWITH | TRANSITIONS OPTICAL INC (US) | 2011-12-14 | — | — | EP | disclosed |
| WO-2011112325-A1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES, NON-AQUEOUS DISPERSIONS THEREOF AND ARTICLES PREPARED THEREWITH | TRANSITIONS OPTICAL, INC. (US) | 2011-09-15 | — | — | WO | disclosed |
| WO-2007140071-A1 | PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070278460-A1 | Photochromic materials comprising metallocenyl groups | TRANSITIONS OPTICAL LIMITED (IE) | 2007-12-06 | — | — | US | disclosed |
| WO-2007140058-A1 | PHOTOCHROMIC MATERIALS COMPRISING METALLOCENYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070278461-A1 | PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | US | disclosed |
| EP-1778815-A1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES, AQUEOUS COMPOSITIONS THEREOF AND ARTICLES PREPARED THEREWITH | TRANSITIONS OPTICAL, INC. (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1776436-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006022825-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006019435-A1 | METHODS FOR PRODUCING PHOTOSENSITIVE MICROPARTICLES, AQUEOUS COMPOSITIONS THEREOF AND ARTICLES PREPARED THEREWITH | TRANSITIONS OPTICAL, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060022176-A1 | Reaction product of a ring-opening cyclic ester or carbonate and a photochromic initiator, especially a naphtho[1,2-b]quinone with one or more hydroxy groups, e.g., (1) 3,3-di(4-methoxyphenyl)-6,7-dimethoxy-13-methyl-13-(2-(2-hydroxyethoxy)ethoxy)-3H,13H-indeno[2,1-f]naphtho[1,2-b]pyran. | TRANSITIONS OPTICAL LIMITED (IE) | 2006-02-02 | — | — | US | disclosed |
| US-20060014099-A1 | Methods for producing photosensitive microparticles, aqueous compositions thereof and articles prepared therewith | ORGANIZATION - WORLD INTELLECTUAL PROPERTY | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070278461-A1 | PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS | TELO2, EYA3, CRY2 | ALDH1A1 2841/4885KDM4E 2611/4885GAA 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.