Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226390 | 0.77 | SNCA (0.56) | LMNASNCAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL615623 | 0.72 | NOTUM (0.61) | LMNAMAPTHTTSIRT2MAPK1 | |
| SCHEMBL5711977 | 0.72 | NOTUM (0.54) | LMNASNCAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1654554 | 0.71 | NOTUM (0.57) | LMNASNCAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10980677 | 0.71 | NOTUM (0.50) | LMNAMAPTHPGD | |
| SCHEMBL11632056 | 0.70 | DPP7 (0.39) | LMNASNCAMAPTKDM4EALDH1A1 | |
| SCHEMBL29358148 | 0.70 | MAPT (0.45) | LMNASNCAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28360647 | 0.70 | NOTUM (0.56) | LMNASNCAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2062244 | 0.70 | NOTUM (0.48) | LMNASNCAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL981641 | 0.70 | NOTUM (0.60) | LMNAMAPTSMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60105604-A | — | — | None | — | — | JP | disclosed |
| JP-S60105604-A | AGRICULTURAL AND HORTICULTURAL FUNGICIDE | IDEMITSU KOSAN CO LTD | 1985-06-11 | — | — | JP | disclosed |