Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580807 | 0.83 | LMNA (0.44) | NOTUMMAPTKDM4EHTTALDH1A1 | |
| SCHEMBL28356954 | 0.78 | NOTUM (0.64) | NOTUMMAPTKDM4EHTTLMNA | |
| SCHEMBL10595973 | 0.77 | MAPT (0.46) | MAPTKDM4EHTTALDH1A1LMNA | |
| SCHEMBL27999083 | 0.77 | MAPT (0.44) | NOTUMMAPTKDM4EHTTALDH1A1 | |
| SCHEMBL28360648 | 0.77 | NOTUM (0.62) | NOTUMMAPT | |
| SCHEMBL26817417 | 0.77 | NOTUM (0.62) | NOTUMHTTALDH1A1 | |
| SCHEMBL11928844 | 0.76 | MAPT (0.46) | MAPTKDM4EHTTALDH1A1LMNA | |
| SCHEMBL21008407 | 0.74 | MAPT (0.45) | NOTUMMAPTKDM4EHTTALDH1A1 | |
| SCHEMBL28360666 | 0.73 | NOTUM (0.57) | NOTUMALDH1A1 | |
| SCHEMBL19795361 | 0.73 | CHRNA7 (0.45) | MAPTKDM4EHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804008-A | 1, 3-disubstituted indoline derivative and preparation method thereof | 陕西科技大学 | 2020-02-18 | — | — | CN | disclosed |