Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615623 | 0.80 | NOTUM (0.61) | MAPTSIRT2LMNADRD4HTR2C | |
| SCHEMBL29360469 | 0.77 | HSD17B3 (0.52) | MAPTKDM4EHTTTHRB | |
| SCHEMBL29359963 | 0.72 | NOTUM (0.59) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7416582 | 0.72 | KDM4E (0.67) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28360647 | 0.72 | NOTUM (0.56) | MAPTKDM4ELMNASNCAALDH1A1 | |
| SCHEMBL2062468 | 0.72 | HTR2C (0.46) | MAPTKDM4ESIRT2LMNADRD4 | |
| SCHEMBL5711977 | 0.71 | NOTUM (0.54) | MAPTKDM4ELMNASNCAALDH1A1 | |
| SCHEMBL981641 | 0.71 | NOTUM (0.60) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7749893 | 0.71 | DRD4 (0.55) | MAPTSIRT2LMNADRD4HTR2C | |
| SCHEMBL27888907 | 0.71 | HTR2C (0.58) | MAPTSIRT2LMNADRD4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022016690-A1 | LUCIFERASE SUBSTRATES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2022-01-27 | — | — | WO | disclosed |