Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503453 | 0.80 | ALDH1A1 (0.30) | — | |
| SCHEMBL392464 | 0.72 | GAA (0.33) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL21173492 | 0.72 | MAPT (0.33) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL17968474 | 0.69 | CYP1A2 (0.33) | — | |
| SCHEMBL8476289 | 0.68 | CHEK1 (0.31) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL10438997 | 0.68 | CHEK1 (0.50) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL1503457 | 0.68 | CHEK1 (0.35) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL9657936 | 0.68 | CHEK1 (0.55) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL10753818 | 0.67 | MAPT (0.37) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| Hydrochloric Acid SCHEMBL28477496 | 0.67 | GAA (0.42) | CHEK1NEK2LIMK1DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047184-B1 | RADIATION POLYMERIZABLE COMPOSITION FOR FORMING HEAT-RESISTANT RELIEF STRUCTURES ON ELECTRICAL DEVICES SUCH AS SEMICONDUCTORS AND CAPACITORS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-09 | — | — | EP | disclosed |
| EP-0047184-A2 | Radiation polymerizable composition for forming heat-resistant relief structures on electrical devices such as semiconductors and capacitors | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-10 | — | — | EP | disclosed |