SCHEMBL1503457

SCHEMBL1503457

Cc1c([SiH3])ccc(N(C)C)c1C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.35
NEK2 P51955 1/20 0.35
LIMK1 P53667 1/20 0.35
DYRK1A Q13627 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
EP300 Q09472 1/20 0.34
KAT2B Q92831 1/20 0.34
KAT8 Q9H7Z6 1/20 0.34
KDM4E B2RXH2 2/20 0.31
GAA P10253 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7902639 0.81
SCHEMBL28011050 0.79
SCHEMBL27928673 0.78 MAPT (0.44) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL21173492 0.74 MAPT (0.33) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL392464 0.74 GAA (0.33) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL765972 0.70 CHEK1 (0.31) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL10438997 0.70 CHEK1 (0.50) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL8476289 0.70 CHEK1 (0.31) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL1503453 0.69 ALDH1A1 (0.30)
SCHEMBL10933423 0.68 CHEK1 (0.30) CHEK1NEK2LIMK1DYRK1ACLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9460912-B2 High temperature atomic layer deposition of silicon oxide thin films AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-10-04 US claimed
US-10941301-B2 Surface treatment method, surface treatment agent, and method for forming film region-selectively on substrate TOKYO OHKA KOGYO CO., LTD. (JP) 2021-03-09 US disclosed
US-20190203054-A1 SURFACE TREATMENT METHOD, SURFACE TREATMENT AGENT, AND METHOD FOR FORMING FILM REGION-SELECTIVELY ON SUBSTRATE TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-04 US disclosed
US-10093815-B2 Surface treatment agent and surface treatment method TOKYO OHKA KOGYO CO., LTD. (JP) 2018-10-09 US disclosed
US-20170088722-A1 SURFACE TREATMENT AGENT AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2017-03-30 US disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20110054184-A1 SURFACE TREATMENT AGENT AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054184-A1 SURFACE TREATMENT AGENT AND SURFACE TREATMENT METHOD ITGA2, ITGA1, ITGAL CHEK1 2934/4885NEK2 2153/4885LIMK1 1737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.