SCHEMBL392464

SCHEMBL392464

Cc1ccc(N(C)C)c(C)c1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.33
MAPT P10636 4/20 0.33
KDM4E B2RXH2 2/20 0.33
CHEK1 O14757 1/20 0.33
NEK2 P51955 1/20 0.33
LIMK1 P53667 1/20 0.33
DYRK1A Q13627 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
EP300 Q09472 1/20 0.32
KAT2B Q92831 1/20 0.32
KAT8 Q9H7Z6 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 4/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PAX8 Q06710 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9814882 0.79 CHEK1 (0.31) GAAMAPTKDM4ECHEK1NEK2
SCHEMBL27498441 0.79 CYP1A2 (0.30) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL21173492 0.78 MAPT (0.33) GAAMAPTKDM4ECHEK1NEK2
SCHEMBL11645323 0.77 ALDH1A1 (0.40) GAAMAPTEP300KAT2BKAT8
SCHEMBL533038 0.77 POLB (0.52) GAAMAPTKDM4ECHEK1NEK2
SCHEMBL27649636 0.77 CHEK1 (0.30) GAAMAPTKDM4ECHEK1NEK2
SCHEMBL1911943 0.76 MAPT (0.48) GAAMAPTKDM4ECHEK1NEK2
SCHEMBL30733276 0.76 MAPT (0.48) GAAMAPTKDM4ECHEK1NEK2
SCHEMBL10933428 0.75 GAA (0.32) GAAMAPTKMT2A
SCHEMBL28939186 0.75 CRHR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 CN claimed
CN-119898789-A Flower-like sphere mordenite as well as preparation method and application thereof 中国石油化工股份有限公司 2025-04-29 CN claimed
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2024-08-27 US claimed
CN-117925054-A Water-based epoxy antirust paint and preparation method thereof 江门市制漆厂有限公司 2024-04-26 CN claimed
CN-111094385-B Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2024-04-09 CN claimed
WO-2022134489-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUND 福建中欣氟材高宝科技有限公司 2022-06-30 WO claimed
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2022-06-30 US claimed
CN-112608212-B Full continuous flow synthesis process of fluorine-containing aromatic compound 福建中欣氟材高宝科技有限公司 2022-02-08 CN claimed
CN-112608212-A Full continuous flow synthesis process of fluorine-containing aromatic compound 福建高宝矿业有限公司 2021-04-06 CN claimed
EP-3718543-A1 PHARMACEUTICAL COMPOSITION AND USE THEREOF Chen, Rong (CN) 2020-10-07 EP claimed
EP-1738737-B1 Dimensionally stable articles from cured condensation-crosslinked dental material KETTENBACH GMBH & CO KG (DE) 2012-05-16 EP claimed
US-20050250871-A1 Dental material based on alkoxysilyl-functional polyethers containing a salt of a strong acid as catalyst KETTENBACH GMBH & CO. KG (DE) 2005-11-10 US claimed
EP-0995421-A2 Light polymerisable single-component dental material Heraeus Kulzer GmbH & Co.KG (DE) 2000-04-26 EP claimed
WO-1997021737-A1 PHOTOINITIATOR COMPOSITION CONTAINING A BORATE SALT AND A HYPERVALENT ATOM-CONTAINING SALT SPECTRA GROUP LIMITED, INC. (US) 1997-06-19 WO claimed
CN-85106252-A The preparation method of compound and application thereof 1986-06-10 CN claimed
JP-9218514-A None JP disclosed
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 CN disclosed
US-4294940-A A CATIONIC POLYMER OF A CONJUGATED DIENE MODIFIED BY AN UNSATURATED ACID OR ANHYDRIDE, ALCOHOL OR AMINE, EPOXY COMPOUND, AND BLOCKED POLYISOCYANATE; AUTO PAINTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-10-13 US disclosed
US-4233055-A Quaternary ammonioalkanecarboxylic acid anilides as plant growth influencing agents CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4141718-A ANTIGROWTH AGENTS FOR PLANTS CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050250871-A1 Dental material based on alkoxysilyl-functional polyethers containing a salt of a strong acid as catalyst SMCHD1, PSKH1, PANK1 GAA 945/4885MAPT 2663/4885KDM4E 1194/4885
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS AHR, FGFR2, FGFR1 GAA 1819/4885MAPT 3161/4885KDM4E 2623/4885
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds AHR, FGFR2, FGFR1 GAA 1819/4885MAPT 3161/4885KDM4E 2623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.