Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932954 | 0.92 | MEN1 (0.41) | LMNAMEN1KMT2AKDM4EHTT | |
| SCHEMBL8859016 | 0.89 | MEN1 (0.45) | LMNAMEN1KMT2AKDM4EPKM | |
| SCHEMBL10937898 | 0.87 | CA2 (0.45) | LMNAMEN1KMT2ANPSR1PKM | |
| SCHEMBL239971 | 0.86 | KDM4E (0.50) | LMNAKDM4ENPSR1HTTCA2 | |
| SCHEMBL10937429 | 0.85 | APP (0.38) | LMNAMEN1KMT2AMMP2 | |
| SCHEMBL10930908 | 0.85 | LMNA (0.42) | LMNAMEN1KMT2AKDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL11409053 | 0.84 | KDM4E (0.48) | LMNAMEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL10935360 | 0.82 | LMNA (0.34) | LMNAMEN1KMT2A | |
| SCHEMBL11429079 | 0.82 | MMP2 (0.52) | LMNAMEN1KMT2AKDM4EPKM | |
| SCHEMBL30039554 | 0.82 | CA1 (0.50) | CA2CA12CA1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518413-A | Poly-phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |