SCHEMBL10933735

SCHEMBL10933735

Nc1ccc(C(=C(c2ccc(N)cc2)c2ccc(N)cc2)c2ccc(N)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 6/20 0.65
▸ MAPT P10636 3/20 0.57
▸ MEN1 O00255 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ MASP2 O00187 1/20 0.55
▸ PLAU P00749 1/20 0.55
▸ THPO P40225 1/20 0.55
▸ ESR1 P03372 3/20 0.54
▸ ESR2 Q92731 3/20 0.54
▸ APEX1 P27695 2/20 0.52
▸ F2 P00734 1/20 0.52
▸ PRSS1 P07477 1/20 0.52
▸ PRSS3 P35030 1/20 0.52
▸ CYP3A4 P08684 5/20 0.50
▸ ALDH1A1 P00352 4/20 0.50
▸ HIF1A Q16665 3/20 0.50
▸ ALOX15 P16050 2/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ CA3 P07451 1/20 0.50
▸ THRB P10828 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11681167 0.88 CYP19A1 (0.54) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL16744514 0.88 CYP19A1 (0.54) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL2566825 0.88 CYP19A1 (0.54) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL15326126 0.88 CYP19A1 (0.54) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL8906711 0.88 CYP19A1 (0.54) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL23071538 0.82 CYP3A4 (0.59) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL11703220 0.82 CYP19A1 (0.68) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL19799420 0.82 HTT (0.56) CYP19A1MAPTMEN1KMT2AMASP2
SCHEMBL28000965 0.82 HSD17B10 (0.64) CYP19A1MAPTMEN1KMT2AESR1
SCHEMBL24023120 0.80 ESR1 (0.61) CYP19A1MAPTMEN1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103405-A1 COF AEROGEL COMPOSITE ADSORBENT FOR PFAS TREATMENT, PREPARATION METHOD AND APPLICATION THEREOF BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY (CN) 2026-04-16 — — US claimed
US-20250003558-A9 Covalent Organic Frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-02 — — US claimed
CN-118290682-A Preparation method of crystalline two-dimensional film 中山大学 2024-07-05 — — CN claimed
CN-118221979-A Preparation method of fluorinated non-planar imine covalent organic framework film 华东理工大学 2024-06-21 — — CN claimed
CN-114773556-B Green solid-phase synthesis method of covalent organic framework material 耀科新材料(苏州)有限公司 2024-06-04 — — CN claimed
CN-117772149-A PUF/COF composite material, preparation method and application thereof 山东威高血液净化制品股份有限公司 2024-03-29 — — CN claimed
CN-117735483-A Photocatalysis method for preparing hundred millimole grade hydrogen peroxide 四川大学 2024-03-22 — — CN claimed
CN-117717902-A Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-03-19 — — CN claimed
CN-117343256-B Functionalized covalent organic framework material and preparation method and application thereof 四川大学 2024-02-13 — — CN claimed
CN-117343256-A Functionalized covalent organic framework material and preparation method and application thereof 四川大学 2024-01-05 — — CN claimed
CN-114773556-A Green solid-phase synthesis method of covalent organic framework material 南开大学 2022-07-22 — — CN claimed
CN-114713286-A Ti-MOFs @ COFs hybrid material with stable core-shell structure and preparation method and application thereof 中南大学 2022-07-08 — — CN claimed
CN-112844049-B COF film material for membrane distillation seawater desalination and preparation method thereof 北京理工大学 2022-05-31 — — CN claimed
CN-114307671-A Preparation method of grafting modified covalent organic framework composite membrane pore channel and filter membrane thereof 天津大学 2022-04-12 — — CN claimed
CN-114214751-A Covalent bond organic framework nanofiber and preparation method and application thereof 南方科技大学 2022-03-22 — — CN claimed
CN-113527729-A Aggregation-induced emission polymer film and macro preparation method thereof 浙江大学 2021-10-22 — — CN claimed
WO-2021142474-A1 COVALENT ORGANIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-07-15 — — WO claimed
CN-112844049-A COF film material for membrane distillation seawater desalination and preparation method thereof 北京理工大学 2021-05-28 — — CN claimed
CN-111808282-A Method for rapidly preparing two-dimensional covalent organic framework material at low temperature and two-dimensional covalent organic framework material 中国地质大学(北京) 2020-10-23 — — CN claimed
CN-110698945-A Environment-friendly glass baking varnish and preparation method thereof 刘艳蕊 2020-01-17 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103405-A1 COF AEROGEL COMPOSITE ADSORBENT FOR PFAS TREATMENT, PREPARATION METHOD AND APPLICATION THEREOF PFAS, BPTF, ETFB CYP19A1 2417/4885MAPT 546/4885MEN1 4368/4885
US-20250003558-A9 Covalent Organic Frameworks EPCAM, VIM, GIGYF2 CYP19A1 3676/4885MAPT 1063/4885MEN1 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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