Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MASP2 | O00187 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681167 | 0.88 | CYP19A1 (0.54) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL16744514 | 0.88 | CYP19A1 (0.54) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL2566825 | 0.88 | CYP19A1 (0.54) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL15326126 | 0.88 | CYP19A1 (0.54) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL8906711 | 0.88 | CYP19A1 (0.54) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL23071538 | 0.82 | CYP3A4 (0.59) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL11703220 | 0.82 | CYP19A1 (0.68) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL19799420 | 0.82 | HTT (0.56) | CYP19A1MAPTMEN1KMT2AMASP2 | |
| SCHEMBL28000965 | 0.82 | HSD17B10 (0.64) | CYP19A1MAPTMEN1KMT2AESR1 | |
| SCHEMBL24023120 | 0.80 | ESR1 (0.61) | CYP19A1MAPTMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103405-A1 | COF AEROGEL COMPOSITE ADSORBENT FOR PFAS TREATMENT, PREPARATION METHOD AND APPLICATION THEREOF | BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY (CN) | 2026-04-16 | — | — | US | claimed |
| US-20250003558-A9 | Covalent Organic Frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-02 | — | — | US | claimed |
| CN-118290682-A | Preparation method of crystalline two-dimensional film | 中山大学 | 2024-07-05 | — | — | CN | claimed |
| CN-118221979-A | Preparation method of fluorinated non-planar imine covalent organic framework film | 华东理工大学 | 2024-06-21 | — | — | CN | claimed |
| CN-114773556-B | Green solid-phase synthesis method of covalent organic framework material | 耀科新材料(苏州)有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117772149-A | PUF/COF composite material, preparation method and application thereof | 山东威高血液净化制品股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117735483-A | Photocatalysis method for preparing hundred millimole grade hydrogen peroxide | 四川大学 | 2024-03-22 | — | — | CN | claimed |
| CN-117717902-A | Preparation method and application of covalent organic framework nanofiltration membrane | 天津大学 | 2024-03-19 | — | — | CN | claimed |
| CN-117343256-B | Functionalized covalent organic framework material and preparation method and application thereof | 四川大学 | 2024-02-13 | — | — | CN | claimed |
| CN-117343256-A | Functionalized covalent organic framework material and preparation method and application thereof | 四川大学 | 2024-01-05 | — | — | CN | claimed |
| CN-114773556-A | Green solid-phase synthesis method of covalent organic framework material | 南开大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114713286-A | Ti-MOFs @ COFs hybrid material with stable core-shell structure and preparation method and application thereof | 中南大学 | 2022-07-08 | — | — | CN | claimed |
| CN-112844049-B | COF film material for membrane distillation seawater desalination and preparation method thereof | 北京理工大学 | 2022-05-31 | — | — | CN | claimed |
| CN-114307671-A | Preparation method of grafting modified covalent organic framework composite membrane pore channel and filter membrane thereof | 天津大学 | 2022-04-12 | — | — | CN | claimed |
| CN-114214751-A | Covalent bond organic framework nanofiber and preparation method and application thereof | 南方科技大学 | 2022-03-22 | — | — | CN | claimed |
| CN-113527729-A | Aggregation-induced emission polymer film and macro preparation method thereof | 浙江大学 | 2021-10-22 | — | — | CN | claimed |
| WO-2021142474-A1 | COVALENT ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-15 | — | — | WO | claimed |
| CN-112844049-A | COF film material for membrane distillation seawater desalination and preparation method thereof | 北京理工大学 | 2021-05-28 | — | — | CN | claimed |
| CN-111808282-A | Method for rapidly preparing two-dimensional covalent organic framework material at low temperature and two-dimensional covalent organic framework material | 中国地质大学(北京) | 2020-10-23 | — | — | CN | claimed |
| CN-110698945-A | Environment-friendly glass baking varnish and preparation method thereof | 刘艳蕊 | 2020-01-17 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103405-A1 | COF AEROGEL COMPOSITE ADSORBENT FOR PFAS TREATMENT, PREPARATION METHOD AND APPLICATION THEREOF | PFAS, BPTF, ETFB | CYP19A1 2417/4885MAPT 546/4885MEN1 4368/4885 |
| US-20250003558-A9 | Covalent Organic Frameworks | EPCAM, VIM, GIGYF2 | CYP19A1 3676/4885MAPT 1063/4885MEN1 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.