Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.79 |
| ▸ | HTT | P42858 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | HPGD | P15428 | 4/20 | 0.79 |
| ▸ | THRB | P10828 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.66 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934745 | 1.00 | MAPT (0.79) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL711570 | 0.89 | ALDH1A1 (1.00) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL16226344 | 0.89 | ALDH1A1 (1.00) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL711571 | 0.89 | ALDH1A1 (1.00) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL11013816 | 0.86 | ALDH1A1 (0.58) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL11013809 | 0.86 | ALDH1A1 (0.58) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL10937052 | 0.83 | MAPT (0.55) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL10937055 | 0.83 | MAPT (0.55) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL28984937 | 0.81 | ALDH1A1 (1.00) | MAPTALDH1A1NPSR1HTTLMNA | |
| SCHEMBL11019488 | 0.79 | ALDH1A1 (0.79) | MAPTALDH1A1NPSR1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4541959-A | ANTICHOLESTEROL | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1985-09-17 | — | — | US | disclosed |
| EP-0136066-A2 | Diphenylsulfide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-04-03 | — | — | EP | disclosed |