Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 3/20 | 0.35 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941845 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL11250295 | 0.76 | NR1H2 (0.32) | HTTNPC1RAB9AMAPTNPSR1 | |
| SCHEMBL7940607 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10978325 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL503539 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL978570 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL765788 | 0.74 | TDP1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL20850551 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KIF11 | |
| SCHEMBL11066182 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL518851 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552984-A | SULFONYLATION IN PRESENCE OF BORON TRIFLUORIDE, HYDROGEN FLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-11-12 | — | — | US | disclosed |
| EP-0085265-B1 | PROCESS FOR THE PREPARATION OF ALPHA,ALPHA-DIFLUOROALKOXY OR ALPHA,ALPHA-DIFLUOROALKYLTHIOPHENYL KETONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-22 | — | — | EP | disclosed |
| EP-0084743-B1 | PROCESS FOR THE PREPARATION OF ALPHA, ALPHA-DIFLUOROALKOXY OR ALPHA, ALPHADIFLUOROALKYLTHIOPHENYL SULFONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-11-21 | — | — | EP | disclosed |
| US-4446078-A | REACTING A POLYHALOALKOXY- OR POLYHALOALKYLTHIOBENZENE WITH A CARBOXYLIC DERIVATIVE, BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4438043-A | Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
| EP-0092627-A1 | Process for the preparation of di- or trifluoromethoxyphenyl ketones or of di- or trifluoromethylthiophenyl ketones | RHONE-POULENC CHIMIE (FR) | 1983-11-02 | — | — | EP | disclosed |
| EP-0085265-A1 | Process for the preparation of alpha,alpha-difluoroalkoxy or alpha,alpha-difluoroalkylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-10 | — | — | EP | disclosed |
| EP-0084743-A1 | Process for the preparation of alpha, alpha-difluoroalkoxy or alpha, alphadifluoroalkylthiophenyl sulfones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-03 | — | — | EP | disclosed |