Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005997 | 0.84 | KCNK2 (0.54) | ALDH1A1KDM4ETDP1PTPRZ1MAPT | |
| SCHEMBL8941503 | 0.80 | LMNA (0.38) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL13950430 | 0.80 | MAPT (0.41) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10935258 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL25118409 | 0.78 | MAPT (0.37) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL7940607 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10978325 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL12436758 | 0.75 | MAOA (0.44) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL28540817 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL16555940 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632892-B1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2024-07-31 | — | — | EP | disclosed |
| CN-110799490-B | 3-arylpropionamide compound and method for producing 3-arylpropionate compound | 住友化学株式会社 | 2023-05-02 | — | — | CN | disclosed |
| US-11028056-B2 | Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-08 | — | — | US | disclosed |
| US-20200165209-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-05-28 | — | — | US | disclosed |
| EP-3632892-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2020-04-08 | — | — | EP | disclosed |
| CN-110799490-A | Process for producing 3-arylpropionamide compound and process for producing 3-arylpropionate compound | 住友化学株式会社 | 2020-02-14 | — | — | CN | disclosed |
| CN-110372550-A | Aryl ether and application thereof | 佩洛通治疗公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105530923-B | Aryl ethers and their use | 佩洛通治疗公司 | 2019-07-23 | — | — | CN | disclosed |
| WO-2015168368-A1 | FLUOROALKYLATION REAGENTS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-11-05 | — | — | WO | disclosed |
| WO-2015168368-A1 | FLUOROALKYLATION REAGENTS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-11-05 | — | — | WO | disclosed |
| US-4446078-A | REACTING A POLYHALOALKOXY- OR POLYHALOALKYLTHIOBENZENE WITH A CARBOXYLIC DERIVATIVE, BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4438043-A | Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
| EP-0023422-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4431808-A | ANTIDEPRESSANTS; TRANQUILIZERS; NEUROLEPTIC AGENTS | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1984-02-14 | — | — | US | disclosed |
| EP-0092627-A1 | Process for the preparation of di- or trifluoromethoxyphenyl ketones or of di- or trifluoromethylthiophenyl ketones | RHONE-POULENC CHIMIE (FR) | 1983-11-02 | — | — | EP | disclosed |
| EP-0085265-A1 | Process for the preparation of alpha,alpha-difluoroalkoxy or alpha,alpha-difluoroalkylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-10 | — | — | EP | disclosed |
| EP-0084743-A1 | Process for the preparation of alpha, alpha-difluoroalkoxy or alpha, alphadifluoroalkylthiophenyl sulfones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-03 | — | — | EP | disclosed |
| EP-0064322-A2 | Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-10 | — | — | EP | disclosed |
| EP-0023422-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-04 | — | — | EP | disclosed |
| US-4020169-A | FROM ARYL IODIDE OR BROMIDE AND TRIFLUOROMETHYL THIO COPPER | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165209-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | AADAC, DDT, NAT1 | ALDH1A1 116/4885KDM4E 1788/4885TDP1 1825/4885 |
| US-11028056-B2 | Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound | AADAC, DDT, NAT1 | ALDH1A1 116/4885KDM4E 1788/4885TDP1 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.