SCHEMBL10935348

SCHEMBL10935348

C[N+](C)(C)CC(OC(=O)O)C(=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CYP1A2 P05177 1/20 0.44
HRH1 P35367 1/20 0.44
SLC22A16 Q86VW1 1/20 0.43
TSHR P16473 4/20 0.42
CHRM2 P08172 2/20 0.42
CHRM4 P08173 2/20 0.42
CHRM1 P11229 2/20 0.42
TBXA2R P21731 1/20 0.42
CYP2C19 P33261 2/20 0.42
RECQL P46063 1/20 0.42
MAPT P10636 4/20 0.41
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP2C9 P11712 2/20 0.41
CPT2 P23786 1/20 0.41
CPT1A P50416 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM3 P20309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15229420 0.73 TSHR (0.68) MEN1KMT2ACYP1A2HRH1SLC22A16
SCHEMBL18553848 0.70 MAPT (0.39) MEN1KMT2ACYP1A2HRH1SLC22A16
SCHEMBL30660559 0.68 SLC22A16 (0.52) MEN1KMT2ACYP1A2HRH1SLC22A16
SCHEMBL29462355 0.68 SLC22A16 (0.52) MEN1KMT2ACYP1A2HRH1SLC22A16
SCHEMBL880674 0.68 MAPT (0.38) MEN1KMT2ACYP1A2HRH1SLC22A16
SCHEMBL22485402 0.68 LMNA (0.72) MEN1KMT2ACYP1A2HRH1TSHR
SCHEMBL13484720 0.68 MAPT (0.38) MEN1KMT2ACYP1A2HRH1SLC22A16
SCHEMBL28233124 0.68 LMNA (0.72) MEN1KMT2ACYP1A2HRH1TSHR
SCHEMBL3047899 0.67 SMN1; SMN2 (0.41) HRH1CHRM1SMN1; SMN2CHRM3TP53
SCHEMBL4783813 0.67 CHRM1 (0.59) MEN1KMT2ACYP1A2HRH1SLC22A16

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60218357-A None JP disclosed
JP-S60218357-A CHOLINE DICARBOXYLATE DERIVATIVE DAINIPPON INK & CHEM INC 1985-11-01 JP disclosed