SCHEMBL10935481

SCHEMBL10935481

Nc1cc(N=Nc2cccc(S(=O)(=O)O)c2)ccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
HSD17B10 Q99714 2/20 0.60
SENP3 Q9H4L4 2/20 0.59
SENP2 Q9HC62 2/20 0.59
SENP1 Q9P0U3 2/20 0.59
SUMO2 P61956 1/20 0.59
SUMO1 P63165 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
TDP1 Q9NUW8 2/20 0.58
GAA P10253 2/20 0.58
MAPT P10636 2/20 0.58
MAPK1 P28482 1/20 0.58
KMT2A Q03164 1/20 0.58
GLO1 Q04760 8/20 0.57
CA12 O43570 4/20 0.57
CA2 P00918 4/20 0.57
CA9 Q16790 4/20 0.57
TSHR P16473 1/20 0.49
POLB P06746 1/20 0.47
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11216562 1.00 ALDH1A1 (0.60) ALDH1A1HSD17B10SENP3SENP2SENP1
SCHEMBL12721244 0.88 SENP3 (0.63) ALDH1A1HSD17B10SENP3SENP2SENP1
SCHEMBL11219752 0.86 HSD17B10 (0.66) ALDH1A1HSD17B10SENP2SUMO2SUMO1
SCHEMBL11578943 0.86 HSD17B10 (0.66) ALDH1A1HSD17B10SENP2SUMO2SUMO1
SCHEMBL3308195 0.83 SENP3 (0.62) ALDH1A1HSD17B10SENP3SENP2SENP1
SCHEMBL3308193 0.83 SENP3 (0.62) ALDH1A1HSD17B10SENP3SENP2SENP1
SCHEMBL5888705 0.83 CA12 (0.73) ALDH1A1HSD17B10SENP3SENP2SENP1
SCHEMBL5888710 0.83 CA12 (0.73) ALDH1A1HSD17B10SENP3SENP2SENP1
SCHEMBL9094890 0.82 SENP2 (0.63) ALDH1A1HSD17B10SENP3SENP2SENP1
SCHEMBL9094885 0.82 SENP2 (0.63) ALDH1A1HSD17B10SENP3SENP2SENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4502865-A Fibre-reactive chromium complex dyes, process for their manufacture and use thereof to dye cellulose or wool CIBA-GEIGY CORPORATION (US) 1985-03-05 US disclosed
US-4432898-A Sulfo-substituted fibre-reactive 1:2-chromium complex azo dyes CIBA-GEIGY CORPORATION (US) 1984-02-21 US disclosed
US-4314937-A FOR POLYAMIDES, WOOL, LEATHER CIBA-GEIGY CORPORATION (US) 1982-02-09 US disclosed
US-4013630-A WOOL, SILK, POLYAMIDES, LEATHER CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed