SCHEMBL10935545

SCHEMBL10935545

CSCOc1cc(OC(=O)N2CCCC2)c(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
TSHR P16473 3/20 0.44
ALDH1A1 P00352 6/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
LMNA P02545 3/20 0.42
HPGD P15428 3/20 0.42
KDM4E B2RXH2 2/20 0.42
GLA P06280 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.41
HTT P42858 1/20 0.41
NPC1 O15118 2/20 0.40
TP53 P04637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL828934 0.80 MAPT (0.55) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL10979237 0.79 MAPT (0.44) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL10977225 0.79 MEN1 (0.46) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL10979209 0.79 MAPT (0.44) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL830223 0.78 TDP1 (0.57) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL29375928 0.78 NPSR1 (0.46) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL10992126 0.78 NPSR1 (0.46) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL10982492 0.78 ALDH1A1 (0.41) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL29375724 0.76 HSP90AA1 (0.51) MAPTNPSR1MEN1KMT2ATDP1
SCHEMBL21062444 0.73 MAPT (0.46) MAPTNPSR1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60218369-A None JP disclosed
JP-S60218369-A SUBSTITUTED PHENYL(THIONO)CARBAMATE AND HERBICIDE CONTAINING SAME AS ACTIVE CONSTITUENT KURARAY CO LTD 1985-11-01 JP disclosed