SCHEMBL10979237

SCHEMBL10979237

C#CCOc1cc(OC(=O)N2CCCC2)c(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
TSHR P16473 3/20 0.42
LMNA P02545 3/20 0.42
HPGD P15428 3/20 0.42
KDM4E B2RXH2 2/20 0.42
GLA P06280 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.41
HTT P42858 1/20 0.41
NPC1 O15118 2/20 0.40
TP53 P04637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10992126 0.99 NPSR1 (0.46) MAPTMEN1KMT2ANPSR1TDP1
SCHEMBL29375928 0.99 NPSR1 (0.46) MAPTMEN1KMT2ANPSR1TDP1
SCHEMBL10999324 0.89 FKBP1A (0.53) MEN1KMT2ANPSR1CYP1A2CYP2C19
SCHEMBL10977725 0.87 LMNA (0.39) MAPTMEN1KMT2ANPSR1CYP1A2
SCHEMBL21062405 0.87 LMNA (0.35) MAPTMEN1KMT2ANPSR1TDP1
SCHEMBL10992627 0.86 LMNA (0.38) MAPTMEN1KMT2ANPSR1TDP1
SCHEMBL10997842 0.84 NPC1 (0.35) MAPTLMNANPC1RAB9A
SCHEMBL10973339 0.84 MEN1 (0.49) MAPTMEN1KMT2ANPSR1TDP1
SCHEMBL16774466 0.84 SMN1; SMN2 (0.49) MAPTMEN1KMT2ANPSR1TDP1
SCHEMBL10993828 0.83 ALDH1A1 (0.51) MAPTMEN1KMT2ANPSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0078099-B1 SUBSTITUTED PHENYL (THIONO)CARBAMATES, HERBICIDAL COMPOSITIONS CONTAINING THE SAME AS ACIVE INGREDIENT AND METHOD OF CONTROLLING WEEDS KURARAY CO., LTD. (JP) 1985-11-27 EP claimed
US-4521242-A Substituted phenyl carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1985-06-04 US claimed
EP-0078099-A2 Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as acive ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1983-05-04 EP claimed
US-20230175004-A1 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN IX OXIDASE OF VARIOUS CYANOBACTERIA OR VARIANT THEREOF Farmhannong Co., Ltd. (KR) 2023-06-08 US disclosed
US-11466286-B2 Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variant thereof Farmhannong Co., Ltd. (KR) 2022-10-11 US disclosed
US-11339404-B2 Protoporphyrinogen oxidase variants and methods and compositions for conferring and/or enhancing herbicide tolerance using the same Farmhannong Co., Ltd. (KR) 2022-05-24 US disclosed
US-20220042033-A1 COMPOSITION AND METHOD FOR CONFERRING AND/OR ENHANCING TOLERANCE AGAINST HERBICIDES BY USING VARIANTS OF PPO Farmhannong Co., Ltd. (KR) 2022-02-10 US disclosed
US-11219221-B2 Composition and method for conferring and/or enhancing herbicide tolerance using variants of protoporphyrinogen IX oxidase from cyanobacteria Farmhannong Co., Ltd. (KR) 2022-01-11 US disclosed
US-20210095305-A1 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN OXIDASE OR VARIANT THEREOF FARMHANNONG CO LTD (KR) 2021-04-01 US disclosed
WO-2020251313-A2 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN IX OXIDASE OF VARIOUS CYANOBACTERIA OR VARIANT THEREOF Farmhannong Co., Ltd. (KR) 2020-12-17 WO disclosed
US-10844395-B2 Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variant thereof Farmhannong Co., Ltd. (KR) 2020-11-24 US disclosed
US-20190330650-A1 PROTOPORPHYRINOGEN OXIDASE VARIANTS AND METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING THE SAME Farmhannong Co., Ltd. (KR) 2019-10-31 US disclosed
US-20190330651-A1 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN OXIDASE OR VARIANT THEREOF Farmhannong Co., Ltd. (KR) 2019-10-31 US disclosed
WO-2019117579-A2 COMPOSITION AND METHOD FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN IX OXIDASE VARIANTS DERIVED FROM SYNECHOCYSTIS 주식회사 팜한농 2019-06-20 WO disclosed
EP-3472185-A1 PROTOPORPHYRINOGEN OXIDASE VARIANTS AND METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING THE SAME Farmhannong Co., Ltd. (KR) 2019-04-24 EP disclosed
EP-3472184-A1 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN OXIDASE OR VARIANT THEREOF Farmhannong Co., Ltd. (KR) 2019-04-24 EP disclosed
WO-2017217794-A1 PROTOPORPHYRINOGEN OXIDASE VARIANTS AND METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING THE SAME Farmhannong Co., Ltd. (KR) 2017-12-21 WO disclosed
WO-2017217793-A1 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN OXIDASE OR VARIANT THEREOF Farmhannong Co., Ltd. (KR) 2017-12-21 WO disclosed
US-4521242-A Substituted phenyl carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1985-06-04 US disclosed