SCHEMBL10992126

SCHEMBL10992126

C#CCOc1cc(OC(=O)N2CCCCC2)c(Cl)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 6/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
MAPT P10636 3/20 0.44
TSHR P16473 3/20 0.44
HPGD P15428 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 3/20 0.44
KDM4E B2RXH2 2/20 0.44
GLA P06280 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
GAA P10253 2/20 0.42
NPC1 O15118 2/20 0.41
TP53 P04637 2/20 0.41
RAB9A P51151 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375928 1.00 NPSR1 (0.46) NPSR1TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL10979237 0.99 MAPT (0.44) NPSR1TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL10999324 0.88 FKBP1A (0.53) NPSR1SMN1; SMN2TSHRHPGDMEN1
SCHEMBL10992627 0.87 LMNA (0.38) NPSR1TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL10977725 0.86 LMNA (0.39) NPSR1ALDH1A1SMN1; SMN2MAPTTSHR
SCHEMBL21062405 0.85 LMNA (0.35) NPSR1TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL10993828 0.84 ALDH1A1 (0.51) NPSR1TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL10989945 0.84 ALDH1A1 (0.51) NPSR1TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL10997842 0.83 NPC1 (0.35) MAPTLMNANPC1RAB9A
SCHEMBL10973339 0.82 MEN1 (0.49) NPSR1TDP1ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4521242-A Substituted phenyl carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1985-06-04 US claimed
EP-0078099-A2 Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as acive ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1983-05-04 EP claimed
US-4521242-A Substituted phenyl carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1985-06-04 US disclosed