Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652751 | 0.76 | GAA (0.58) | KMT2AMEN1NPC1RAB9A | |
| Tolfamide SCHEMBL11435090 | 0.76 | HPGD (0.55) | NPC1RAB9A | |
| Tolfamide SCHEMBL29388345 | 0.76 | HPGD (0.55) | NPC1RAB9A | |
| SCHEMBL466508 | 0.76 | MAPT (0.52) | PLK1KMT2AHDAC8ATMMMP3 | |
| SCHEMBL1504747 | 0.74 | HDAC3 (0.54) | KMT2AHDAC8MEN1HDAC3HDAC1 | |
| SCHEMBL8653738 | 0.72 | LMNA (0.64) | HDAC3HDAC1 | |
| SCHEMBL13520263 | 0.71 | PLK1 (0.72) | PLK1HDAC8MMP3NSD2BRD4 | |
| SCHEMBL10930839 | 0.71 | PTPN1 (0.51) | PLK1HDAC8MMP3DEGS1HDAC3 | |
| SCHEMBL8712796 | 0.71 | CTSD (0.68) | KMT2AMEN1KDM4E | |
| SCHEMBL8631381 | 0.71 | OGG1 (0.43) | KMT2AHDAC8ATMMEN1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518413-A | Poly-phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |