Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.59 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.53 |
| ▸ | CLK1 | P49759 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928965 | 0.89 | DYRK1A (0.75) | DYRK1AFSCN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9892912 | 0.88 | RAB9A (0.68) | DYRK1AFSCN1IDO1NPC1RAB9A | |
| SCHEMBL9893066 | 0.86 | DYRK1A (0.78) | DYRK1AFSCN1IDO1NPC1RAB9A | |
| SCHEMBL10935986 | 0.85 | DYRK1A (0.74) | DYRK1ANPC1RAB9ASMN1; SMN2CLK1 | |
| SCHEMBL10596662 | 0.83 | RAB9A (0.65) | DYRK1ANPC1RAB9ASMN1; SMN2CLK1 | |
| SCHEMBL3933070 | 0.80 | DYRK1A (0.72) | DYRK1ANPC1RAB9ASMN1; SMN2CSNK1D | |
| SCHEMBL9891796 | 0.80 | NPC1 (0.59) | DYRK1AFSCN1IDO1NPC1RAB9A | |
| SCHEMBL9891513 | 0.80 | NPC1 (0.57) | DYRK1AFSCN1IDO1NPC1RAB9A | |
| SCHEMBL10936135 | 0.79 | RAB9A (0.50) | DYRK1ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10871355 | 0.78 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051560-B1 | MONOAZOPIGMENTS CONTAINING HETEROCYCLIC NUCLEI, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4400319-A | Monoazo pigments containing heterocycles, and high-molecular organic materials dyed therewith | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0051560-A1 | Monoazopigments containing heterocyclic nuclei, their preparation and use | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |