SCHEMBL10936256

SCHEMBL10936256

NCC(=O)CO[PH](=O)OCC(=O)CN

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.35
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10936261 0.82
SCHEMBL11532528 0.78 GABRR1 (0.31) GABRR1KDM4ELMNA
SCHEMBL8623840 0.76
SCHEMBL11293240 0.74 TDP1 (0.45)
SCHEMBL28418508 0.74 TSHR (0.32)
SCHEMBL11424757 0.73 HTR2C (0.33) KDM4ELMNA
SCHEMBL162388 0.72 KDM4E (0.33) KDM4ELMNA
SCHEMBL6376204 0.72 HPGD (0.31)
SCHEMBL28661378 0.70 ALDH1A1 (0.39)
SCHEMBL347044 0.69 TSHR (0.43) LMNAGLRA1SLC6A9OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0073574-B1 PHOSPHONIUM SALTS OF N-PHOSPHONOMETHYLGLYCINE, PREPARATION AND COMPOSITIONS THEREOF AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULANTS STAUFFER CHEMICAL COMPANY (US) 1985-11-13 EP claimed
EP-0073574-A1 Phosphonium salts of N-phosphonomethylglycine, preparation and compositions thereof and the use thereof as herbicides and plant growth regulants STAUFFER CHEMICAL COMPANY (US) 1983-03-09 EP claimed
EP-0073574-B1 PHOSPHONIUM SALTS OF N-PHOSPHONOMETHYLGLYCINE, PREPARATION AND COMPOSITIONS THEREOF AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULANTS STAUFFER CHEMICAL COMPANY (US) 1985-11-13 EP disclosed
US-4525202-A Phosphonium salts of N-phosphonomethylglycine and their use as herbicides and plant growth regulants STAUFFER CHEMICAL CO. (US) 1985-06-25 US disclosed
EP-0073574-A1 Phosphonium salts of N-phosphonomethylglycine, preparation and compositions thereof and the use thereof as herbicides and plant growth regulants STAUFFER CHEMICAL COMPANY (US) 1983-03-09 EP disclosed
US-4148624-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1979-04-10 US disclosed