Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CTH | P32929 | 1/20 | 0.43 |
| ▸ | CBS | P35520 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524602 | 0.79 | — | — | |
| SCHEMBL10942864 | 0.77 | — | — | |
| SCHEMBL10942913 | 0.75 | TSHR (0.38) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL7889547 | 0.73 | — | — | |
| SCHEMBL3360709 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL162388 | 0.73 | KDM4E (0.33) | THPOALOX15LMNACYP2C19 | |
| Butane SCHEMBL10785306 | 0.71 | PAM (0.36) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL434357 | 0.71 | LMNA (0.42) | TSHRLMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL7783931 | 0.68 | KDM4E (0.41) | — | |
| SCHEMBL4072646 | 0.67 | LMNA (0.48) | TSHRTHRBLMNAALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10256169-B2 | Semiconductor device | FUJI ELECTRIC CO., LTD. (JP) | 2019-04-09 | — | — | US | claimed |
| EP-1019418-B1 | INOSITOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | BIONERIS AB (SE) | 2004-04-28 | — | — | EP | claimed |
| US-4550209-A | REACTING TETRAVALENT ZIRCONIUM COMPOUND WITH ORGANO PHOSPHONIC ACID OR ESTER | TEXACO INC. (US) | 1985-10-29 | — | — | US | claimed |
| US-10256169-B2 | Semiconductor device | FUJI ELECTRIC CO., LTD. (JP) | 2019-04-09 | — | — | US | disclosed |
| US-20170278771-A1 | SEMICONDUCTOR DEVICE | FUJI ELECTRIC CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20120012779-A1 | TEMPERATURE ADJUSTMENT DEVICE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
| CN-101164618-A | A combination of fbpase inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2008-04-23 | — | — | CN | disclosed |
| CN-101125864-A | Heteroaromatic inhibitor for fructose-1,6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2008-02-20 | — | — | CN | disclosed |
| CN-100352505-C | Combination of FBP enzyme inhibitors and insulin sensitizers for the treatment of diabetes | METABASIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | disclosed |
| CN-100349904-C | Novel heteroaromatic inhibitors of fructose-1, 6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-1900087-A | Novel heteroaromatic inhibitors of fructose 1,6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2007-01-24 | — | — | CN | disclosed |
| EP-0213681-A1 | Composite material | AKZO N.V. (NL) | 1987-03-11 | — | — | EP | disclosed |
| US-4550209-A | REACTING TETRAVALENT ZIRCONIUM COMPOUND WITH ORGANO PHOSPHONIC ACID OR ESTER | TEXACO INC. (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0159053-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1985-10-23 | — | — | EP | disclosed |
| US-4483970-A | BLOCK POLYMERS, MOLDING MATERIALS | AKZO N.V. (NL) | 1984-11-20 | — | — | US | disclosed |
| EP-0102115-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1984-03-07 | — | — | EP | disclosed |
| EP-0013461-B1 | PROCESS FOR THE PREPARATION OF A SEGMENTED THERMOPLASTIC ELASTOMER | AKZO N.V. (NL) | 1983-04-06 | — | — | EP | disclosed |
| EP-0013461-A1 | Process for the preparation of a segmented thermoplastic elastomer | AKZO N.V. (NL) | 1980-07-23 | — | — | EP | disclosed |
| US-4138432-A | Amides of phosphonoacetic acid | ABBOTT LABORATORIES (US) | 1979-02-06 | — | — | US | disclosed |
| US-4087522-A | Amides of phosphonoacetic acid for treating herpes simplex virus type 1 and 2 infections | ABBOTT LABORATORIES (US) | 1978-05-02 | — | — | US | disclosed |