SCHEMBL162388

SCHEMBL162388

NC(=O)CO[PH](=O)OCC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
THPO P40225 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11171976 0.80
SCHEMBL10511841 0.78
SCHEMBL10388719 0.78
SCHEMBL347044 0.73 TSHR (0.43) LMNAALOX15CYP2C19THPO
Butane SCHEMBL9844530 0.72 ALOX15 (0.32) ALOX15
SCHEMBL10936256 0.72 GABRR1 (0.35) KDM4ELMNA
SCHEMBL28596526 0.71
SCHEMBL3360709 0.71 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL29103814 0.70 TPI1 (0.46)
SCHEMBL19460311 0.69 KDM4E (0.39) KDM4EGMNNUSP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003747-A Compound for inhibiting FGFR4 kinase and application thereof 察略盛医药科技(上海)有限公司 2023-11-07 CN disclosed
US-10130932-B2 Organic-inorganic hybrid material of use for extracting uranium (VI) from aqueous media containing phosphoric acid, processes for preparing same and uses thereof COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2018-11-20 US disclosed
US-10006103-B2 Use of an organic-inorganic hybrid material for extracting uranium(VI) from a sulfuric acid aqueous solution, issued notably from the sulfuric leaching of a uranium-bearing ore COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2018-06-26 US disclosed
CN-104072542-B Amide phosphonic acid metal complex, corresponding composite material and preparation methods thereof 四川师范大学 2017-01-25 CN disclosed
US-20160289796-A1 USE OF AN ORGANIC-INORGANIC HYBRID MATERIAL FOR EXTRACTING URANIUM(VI) FROM A SULFURIC ACID AQUEOUS SOLUTION, ISSUED NOTABLY FROM THE SULFURIC LEACHING OF A URANIUM-BEARING ORE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2016-10-06 US disclosed
US-20160016150-A1 ORGANIC-INORGANIC HYBRID MATERIAL OF USE FOR EXTRACTING URANIUM (VI) FROM AQUEOUS MEDIA CONTAINING PHOSPHORIC ACID, PROCESSES FOR PREPARING SAME AND USES THEREOF UNIVERSITÉ DE MONTPELLIER (FR) 2016-01-21 US disclosed
US-20140249102-A1 Topical Applicator Composition and Process for Treatment of Radiologically Contaminated Dermal Injuries BATTELLE MEMORIAL INSTITUTE (US) 2014-09-04 US disclosed
WO-2014127860-A1 ORGANIC-INORGANIC HYBRID MATERIAL OF USE FOR EXTRACTING URANIUM(VI) FROM AQUEOUS MEDIA CONTAINING PHOSPHORIC ACID, PROCESSES FOR PREPARING SAME AND USES THEREOF Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2014-08-28 WO disclosed
WO-2012030429-A1 TOPICAL APPLICATOR COMPOSITION AND PROCESS FOR REMOVAL OF RADIONUCLIDES FROM RADIOLOGICALLY CONTAMINATED DERMAL SURFACES BATTELLE MEMORIAL INSTITUTE (US) 2012-03-08 WO disclosed
US-20110110985-A1 FUNCTIONALIZED NANOMATERIALS FOR CHELATION THERAPIES AND SORBENT DIALYSIS OF TOXINS BATTELLE MEMORIAL INSTITUTE (US) 2011-05-12 US disclosed
US-7776611-B2 Optical sensor using functionalized composite materials QUEEN'S UNIVERSITY AT KINGSTON (CA) 2010-08-17 US disclosed
EP-1960487-A1 OPTICAL SENSOR USING FUNCTIONALIZED COMPOSITE MATERIALS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2008-08-27 EP disclosed
US-20070184557-A1 Optical sensor using functionalized composite materials QUEEN'S UNIVERSITY AT KINGSTON (CA) 2007-08-09 US disclosed
WO-2007065268-A1 OPTICAL SENSOR USING FUNCTIONALIZED COMPOSITE MATERIALS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2007-06-14 WO disclosed
US-4904813-A Cyanomethyl acid halides of phosphorus and process for their preparation HOECHST AKTEINGESELLSCHAFT (DE) 1990-02-27 US disclosed