SCHEMBL10936381

SCHEMBL10936381

CC(CO)CP(=O)(CCCO)CCCO

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.38
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10938353 0.96 TRPM8 (0.42) TRPM8TSHR
SCHEMBL1221995 0.82 TRPM8 (0.56) TRPM8TSHR
SCHEMBL2694918 0.81 TSHR (0.39) TRPM8TSHR
SCHEMBL11300305 0.77 TSHR (0.36) TSHR
SCHEMBL1085822 0.72 TYMS (0.37) TSHR
Water SCHEMBL11146050 0.70 TYMS (0.35) TSHR
SCHEMBL1086382 0.69 ALDH1A1 (0.38) TRPM8TSHR
SCHEMBL1085805 0.69 ALDH1A1 (0.38) TRPM8TSHR
SCHEMBL3014053 0.68 PPARD (0.35)
SCHEMBL3022385 0.68 GPR84 (0.33) TRPM8TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0037383-B1 TRIS-(3-HYDROXYALKYL) PHOSPHINE OXIDE FLAME RETARDANT COMPOSITIONS FMC Corporation (US) 1984-11-14 EP claimed
EP-0067424-A2 Flame retardant polyphenylene ether resin compositions FMC Corporation (US) 1982-12-22 EP claimed
US-4357433-A HYDROXYALKYLPHOSPHINE OXIDE FMC CORPORATION (US) 1982-11-02 US claimed
EP-0040665-A1 Flame retardant polyphenylene oxide composition FMC Corporation (US) 1981-12-02 EP claimed
US-4301057-A FOR THERMOPLASTIC GLASS FILLED POLYAMIDES FMC CORPORATION (US) 1981-11-17 US claimed
EP-0037383-A1 Tris-(3-hydroxyalkyl) phosphine oxide flame retardant compositions FMC Corporation (US) 1981-10-07 EP claimed
US-4287119-A CONTAINING POLYPHENYLENE OXIDE FMC CORPORATION (US) 1981-09-01 US claimed
CN-113195576-A Process for preparing halogen-free flame-retardant aqueous polyurethane dispersions 斯塔尔国际有限公司 2021-07-30 CN disclosed
EP-0085201-B1 FLAME RETARDANT POLYPHENYLENE ETHER-STYRENE THERMOPLASTIC RESIN COMPOSITIONS FMC Corporation (US) 1985-09-11 EP disclosed
EP-0037383-B1 TRIS-(3-HYDROXYALKYL) PHOSPHINE OXIDE FLAME RETARDANT COMPOSITIONS FMC Corporation (US) 1984-11-14 EP disclosed
US-4446265-A TRIARYL PHOSPHATE, 3-HYDROXYPROPYLPHOSPHINE OXIDE FMC CORPORATION (US) 1984-05-01 US disclosed
EP-0085201-A1 Flame retardant polyphenylene ether-styrene thermoplastic resin compositions FMC Corporation (US) 1983-08-10 EP disclosed
EP-0074345-A1 Flame retardant polyphenylene ether-styrene thermoplastic resin compositions FMC Corporation (US) 1983-03-16 EP disclosed
EP-0067424-A2 Flame retardant polyphenylene ether resin compositions FMC Corporation (US) 1982-12-22 EP disclosed
US-4357433-A HYDROXYALKYLPHOSPHINE OXIDE FMC CORPORATION (US) 1982-11-02 US disclosed
EP-0040665-A1 Flame retardant polyphenylene oxide composition FMC Corporation (US) 1981-12-02 EP disclosed
US-4301057-A FOR THERMOPLASTIC GLASS FILLED POLYAMIDES FMC CORPORATION (US) 1981-11-17 US disclosed
EP-0037383-A1 Tris-(3-hydroxyalkyl) phosphine oxide flame retardant compositions FMC Corporation (US) 1981-10-07 EP disclosed
US-4287119-A CONTAINING POLYPHENYLENE OXIDE FMC CORPORATION (US) 1981-09-01 US disclosed