SCHEMBL10936799

SCHEMBL10936799

OC1CC(Cc2ccc(F)cc2)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.37
TRPA1 O75762 1/20 0.37
KDM1A O60341 2/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
HTR1A P08908 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HTR2C P28335 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10938285 1.00 HTR6 (0.37) HTR6TRPA1KDM1AMAOAMAOB
SCHEMBL10938290 1.00 HTR6 (0.37) HTR6TRPA1KDM1AMAOAMAOB
SCHEMBL10936618 0.85 LTB4R (0.44) HTR6
SCHEMBL10936608 0.85 LTB4R (0.44) HTR6
SCHEMBL10936612 0.85 LTB4R (0.44) HTR6
SCHEMBL10935032 0.82 TRPA1 (0.41) TRPA1KDM1AMAOAMAOB
SCHEMBL10935029 0.82 TRPA1 (0.41) TRPA1KDM1AMAOAMAOB
SCHEMBL10935038 0.82 TRPA1 (0.41) TRPA1KDM1AMAOAMAOB
SCHEMBL13050936 0.78 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3HTR2C
SCHEMBL13050941 0.78 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4528408-A Trans-3-substituted-1-indanol and insecticidal ester derivatives FMC CORPORATION (US) 1985-07-09 US disclosed
US-4362744-A Trans-3-substituted-1-indanol insecticidal ester derivatives FMC CORPORATION (US) 1982-12-07 US disclosed