Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722048 | 0.84 | CCNB2 (0.58) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL10937675 | 0.80 | HPGD (0.53) | ESR1ESR2NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL18787054 | 0.77 | ESR1 (0.87) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL3929385 | 0.76 | ESR1 (0.63) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL29799621 | 0.76 | ESR1 (1.00) | ESR1ESR2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL31501148 | 0.76 | ALDH1A1 (0.50) | ESR1ESR2CYP19A1ALDH1A1HSD17B10 | |
| SCHEMBL27293850 | 0.76 | ESR1 (0.63) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL3864662 | 0.76 | ESR1 (1.00) | ESR1ESR2CYP19A1ALDH1A1KDM4E | |
| SCHEMBL2826858 | 0.74 | ESR1 (0.61) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL31681138 | 0.74 | ESR1 (0.61) | ESR1ESR2CYP19A1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230874-B | Safety protection boot for preventing toxicity and radiation | 际华三五三九制鞋有限公司 | 2023-08-25 | — | — | CN | claimed |
| US-4415350-A | ROOTING; TREES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF AGRICULTURE (US) | 1983-11-15 | — | — | US | claimed |
| CN-114874603-B | Composite material based on polyimide nanofiber and preparation method thereof | 扬州市天宇鞋业有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-4522808-A | Anti-sunburn compositions containing 2-phenyl-indole derivatives | SOCIETE ANONYME DITE: L'OREAL (FR) | 1985-06-11 | — | — | US | disclosed |