Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.63 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | MPI | P34949 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627825 | 0.86 | SERPINE1 (0.62) | ESR1ESR2SERPINE1MAPTALDH1A1 | |
| SCHEMBL30165919 | 0.86 | SERPINE1 (0.62) | ESR1ESR2SERPINE1MAPTALDH1A1 | |
| SCHEMBL29353160 | 0.85 | ALDH1A1 (0.64) | ESR1ESR2MAPTALDH1A1KDM4E | |
| SCHEMBL13698928 | 0.85 | ALDH1A1 (0.64) | ESR1ESR2MAPTALDH1A1KDM4E | |
| SCHEMBL29159567 | 0.80 | MAPT (0.47) | ESR1ESR2SERPINE1MAPTALDH1A1 | |
| SCHEMBL30416979 | 0.80 | MAPT (0.47) | ESR1ESR2SERPINE1MAPTALDH1A1 | |
| SCHEMBL18787054 | 0.79 | ESR1 (0.87) | ESR1ESR2MAPTALDH1A1KDM4E | |
| SCHEMBL27930779 | 0.77 | ALDH1A1 (0.55) | ESR1ESR2MAPTALDH1A1KDM4E | |
| SCHEMBL3864662 | 0.77 | ESR1 (1.00) | ESR1ESR2ALDH1A1KDM4ECYP19A1 | |
| SCHEMBL29799621 | 0.77 | ESR1 (1.00) | ESR1ESR2ALDH1A1KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9891237-B2 | Fluorescent sensor for metal cation detection based on 2-(2′-hydroxyphenyl)benzazole containing a Schiff base moiety | THE UNIVERSITY OF AKRON (US) | 2018-02-13 | — | — | US | claimed |
| US-20150031067-A1 | NOVEL FLUORESCENT SENSOR FOR METAL CATION DETECTION BASED ON 2-(2'-HYDROXYPHENYL)BENZAZOLE CONTAINING A SCHIFF BASE MOIETY | THE UNIVERSITY OF AKRON | 2015-01-29 | — | — | US | claimed |
| EP-0983334-A1 | ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION | Call, Krimhild (DE) | 2000-03-08 | — | — | EP | claimed |
| WO-1998051772-A1 | ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION | CALL, KRIMHILD (DE) | 1998-11-19 | — | — | WO | claimed |
| US-3995157-A | Surface flaw detection | GENERAL ELECTRIC COMPANY (US) | 1976-11-30 | — | — | US | claimed |
| CN-104725296-B | Indole derivatives and its application in field of organic electroluminescence | 北京鼎材科技有限公司 | 2019-11-29 | — | — | CN | disclosed |
| US-9891237-B2 | Fluorescent sensor for metal cation detection based on 2-(2′-hydroxyphenyl)benzazole containing a Schiff base moiety | THE UNIVERSITY OF AKRON (US) | 2018-02-13 | — | — | US | disclosed |
| US-9891237-B2 | Fluorescent sensor for metal cation detection based on 2-(2′-hydroxyphenyl)benzazole containing a Schiff base moiety | THE UNIVERSITY OF AKRON (US) | 2018-02-13 | — | — | US | disclosed |
| US-20150031067-A1 | NOVEL FLUORESCENT SENSOR FOR METAL CATION DETECTION BASED ON 2-(2'-HYDROXYPHENYL)BENZAZOLE CONTAINING A SCHIFF BASE MOIETY | THE UNIVERSITY OF AKRON | 2015-01-29 | — | — | US | disclosed |
| US-20150031067-A1 | NOVEL FLUORESCENT SENSOR FOR METAL CATION DETECTION BASED ON 2-(2'-HYDROXYPHENYL)BENZAZOLE CONTAINING A SCHIFF BASE MOIETY | THE UNIVERSITY OF AKRON | 2015-01-29 | — | — | US | disclosed |
| US-7507835-B2 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD. (IN) | 2009-03-24 | — | — | US | disclosed |
| US-20060173193-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2006-08-03 | — | — | US | disclosed |
| EP-0983334-A1 | ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION | Call, Krimhild (DE) | 2000-03-08 | — | — | EP | disclosed |
| WO-1999001607-A2 | ENZYMATIC OXIDATION SYSTEM WITH NOVEL ENZYMATIC-EFFECT ENHANCING COMPOUNDS | CALL, KRIMHILD (DE) | 1999-01-14 | — | — | WO | disclosed |
| WO-1998051772-A1 | ENZYMATIC BLEACHING SYSTEM CONTAINING NEW COMPOUNDS FOR INTENSIFYING ENZYMATIC ACTION | CALL, KRIMHILD (DE) | 1998-11-19 | — | — | WO | disclosed |
| EP-0845026-A1 | MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES | CALL, Hans-Peter Dr. (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997048786-A1 | MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES | CALL HANS PETER (DE) | 1997-12-24 | — | — | WO | disclosed |
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |
| US-5298189-A | Fluorescent compound dispersed in polymer matrix, no self-absorption, stable to high energy radiation | NANOPTICS INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| US-3995157-A | Surface flaw detection | GENERAL ELECTRIC COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031067-A1 | NOVEL FLUORESCENT SENSOR FOR METAL CATION DETECTION BASED ON 2-(2'-HYDROXYPHENYL)BENZAZOLE CONTAINING A SCHIFF BASE MOIETY | CNBP, CA2, HELZ | ESR1 3165/4885ESR2 2573/4885SERPINE1 4781/4885 |
| US-20060173193-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | HTR3C, HTR3A, AANAT | ESR1 2095/4885ESR2 2031/4885SERPINE1 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.