Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276835 | 0.80 | ESR1 (0.41) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL11656506 | 0.80 | ALDH1A1 (0.53) | CYP19A1ALDH1A1HSD17B10HTR2AKCNH2 | |
| SCHEMBL31047669 | 0.78 | SERPINE1 (0.65) | ESR1ESR2NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL18787054 | 0.77 | ESR1 (0.87) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL29799621 | 0.76 | ESR1 (1.00) | ESR1ESR2CYP19A1ALDH1A1HTR2A | |
| SCHEMBL3864662 | 0.76 | ESR1 (1.00) | ESR1ESR2CYP19A1ALDH1A1HTR2A | |
| SCHEMBL3929385 | 0.76 | ESR1 (0.63) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL27293850 | 0.76 | ESR1 (0.63) | ESR1ESR2CYP19A1NPSR1ALDH1A1 | |
| SCHEMBL18154508 | 0.75 | ESR1 (0.79) | ESR1ESR2EGFRPTGS2 | |
| SCHEMBL29206325 | 0.75 | MAPT (0.65) | ESR1ESR2NPSR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336924-B | Method for catalyzing green cyanation of halogenated aromatic hydrocarbon by supported Pd complex | 大连理工大学 | 2021-01-19 | — | — | CN | claimed |
| CN-109336924-B | Method for catalyzing green cyanation of halogenated aromatic hydrocarbon by supported Pd complex | 大连理工大学 | 2021-01-19 | — | — | CN | disclosed |
| CN-104725296-B | Indole derivatives and its application in field of organic electroluminescence | 北京鼎材科技有限公司 | 2019-11-29 | — | — | CN | disclosed |
| US-10246414-B2 | Allosteric modulators of CB1 cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2019-04-02 | — | — | US | disclosed |
| EP-2800569-B1 | ALLOSTERIC MODULATORS OF CB1 CANNABINOID RECEPTORS | UNIV NORTHEASTERN (US) | 2018-07-25 | — | — | EP | disclosed |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2017-07-13 | — | — | US | disclosed |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2017-07-13 | — | — | US | disclosed |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2017-07-13 | — | — | US | disclosed |
| US-9556118-B2 | Allosteric modulators of CB1 cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556118-B2 | Allosteric modulators of CB1 cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |
| EP-2253315-A1 | Alkoxyphenylpropanoic acid derivatives | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7786165-B2 | Aminophenylpropanoic acid derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-31 | — | — | US | disclosed |
| US-7517910-B2 | Alkoxyphenylpropanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20070213364-A1 | Alkoxyphenylpropanoic Acid Derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1731505-A1 | ALKOXYPHENYLPROPANOIC ACID DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2006-12-13 | — | — | EP | disclosed |
| EP-1726580-A1 | AMINOPHENYLPROPANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2006-11-29 | — | — | EP | disclosed |
| EP-1303508-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |
| WO-2002006273-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246414-B2 | Allosteric modulators of CB1 cannabinoid receptors | CNR1, CNR2, GPR18 | ESR1 726/4885ESR2 723/4885CYP19A1 2487/4885 |
| US-20070213364-A1 | Alkoxyphenylpropanoic Acid Derivatives | GPR119, FFAR1, GPR55 | ESR1 357/4885ESR2 932/4885CYP19A1 842/4885 |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | GPR119, GPR55, GPR65 | ESR1 358/4885ESR2 733/4885CYP19A1 576/4885 |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | CNR1, CNR2, GPR18 | ESR1 726/4885ESR2 723/4885CYP19A1 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.