Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378190 | 1.00 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL20553469 | 0.85 | ACE2 (0.46) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8859861 | 0.85 | GPR84 (0.50) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL27000032 | 0.84 | GPR84 (0.48) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL19924838 | 0.83 | NOD1 (0.45) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7651250 | 0.80 | GPR84 (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL11220090 | 0.77 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL17024089 | 0.77 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL11351874 | 0.77 | ACE (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL11351867 | 0.77 | ACE (0.44) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593043-A | Mercapto acyl-carnitines and pharmaceutical compositions containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1986-06-03 | — | — | US | disclosed |
| US-4510318-A | DETOXIFICATION; BURN INJURIES; MUCOLYTIC AGENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1985-04-09 | — | — | US | disclosed |