Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351874 | 1.00 | ACE (0.44) | ACEMAPTKDM4ETHRBALOX15 | |
| SCHEMBL10937100 | 0.77 | GPR84 (0.47) | ACEMAPTKDM4ETHRBALOX15 | |
| SCHEMBL11378190 | 0.77 | GPR84 (0.47) | ACEMAPTKDM4ETHRBALOX15 | |
| SCHEMBL8859861 | 0.76 | GPR84 (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL20553469 | 0.76 | ACE2 (0.46) | ACEMAPTKDM4ETHRBALOX15 | |
| SCHEMBL19924838 | 0.75 | NOD1 (0.45) | ACEMAPTKDM4ETHRBALOX15 | |
| SCHEMBL6238817 | 0.74 | CA2 (0.52) | ACEMAPTMMECA2MAPK1 | |
| SCHEMBL28557048 | 0.73 | KDM4E (0.46) | ACEMAPTKDM4ETHRBALOX15 | |
| SCHEMBL7259700 | 0.72 | ACE (0.59) | ACEMAPTKDM4ETHRBALOX15 | |
| SCHEMBL29848957 | 0.72 | KDM4E (0.54) | ACEMAPTKDM4ETHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4305958-A | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1981-12-15 | — | — | US | claimed |