SCHEMBL109380

SCHEMBL109380

Nc1cc(Br)ccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29849481 1.00
SCHEMBL57179 0.79
Hydrochloric Acid SCHEMBL27652041 0.77 ALDH1A1 (0.54)
Bromide SCHEMBL9352122 0.77 ALDH1A1 (0.54)
SCHEMBL28871014 0.76 ALDH1A1 (0.48)
SCHEMBL13663 0.75
SCHEMBL505542 0.75
SCHEMBL29388695 0.75
SCHEMBL29394596 0.75
Hydrochloric Acid SCHEMBL1795985 0.72 KDM4E (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-112500260-B Preparation method of 2-fluoro-5-bromoiodobenzene 山东瑞辰新材料有限公司 2022-12-27 CN claimed
CN-104530107-B A kind of synthetic method of 3-amino-4-fluorobenzoic boric acid 大连联化化学有限公司 2016-08-24 CN claimed
CN-104530107-A Synthetic method for 3-amino-4-fluorophenylboronic acid LIANHUA CHEMISTRY CO LTD DALIAN 2015-04-22 CN claimed
CN-101445460-B Method for preparing 2-fluoride-5-alkoxyl aniline BINHAI KANGJIE CHEMICAL CO LTD 2011-11-16 CN claimed
CN-101450906-B Method for preparing 3-amino-4-fluorophenol TAIXING CHEMSPEC CHEMICALS CO LTD 2011-06-22 CN claimed
CN-101450906-A Method for preparing 3-amino-4-fluorophenol TAIXING KANGPENG CHEMICALS CO (CN) 2009-06-10 CN claimed
CN-101445460-A Method for preparing 2-fluoride-5-alkoxyl aniline BINHAI KANGJIE CHEMICAL CO LTD (CN) 2009-06-03 CN claimed
US-20260103474-A1 NOVEL COMPOUNDS FOR THE DIAGNOSIS OF TDP-43 PROTEINOPATHIES AC IMMUNE SA (CH) 2026-04-16 US disclosed
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
EP-4722209-A1 PROTAC COMPOUND TARGETING ESTROGEN RECEPTOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Beijing Shenogen Pharma Group (CN) 2026-04-08 EP disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260062425-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF GENENTECH INC (US) 2026-03-05 US disclosed
US-12565490-B2 Inhibitors of Receptor Interacting Protein Kinase I for the treatment of disease BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-03 US disclosed
WO-2002074773-A1 IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 2002-09-26 WO disclosed
US-6235740-B1 AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS BRISTOL-MYERS SQUIBB CO. 2001-05-22 US disclosed
WO-1999009845-A1 IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-03-04 WO disclosed
US-4870218-A Trihalobenzene compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-26 US disclosed
US-4788349-A Halogenated diphenyl ether derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-29 US disclosed
EP-0252592-A1 Halogenated diphenyl ether derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-01-13 EP disclosed