⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109380 | 1.00 | — | — | |
| SCHEMBL57179 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27652041 | 0.77 | ALDH1A1 (0.54) | — | |
| Bromide SCHEMBL9352122 | 0.77 | ALDH1A1 (0.54) | — | |
| SCHEMBL28871014 | 0.76 | ALDH1A1 (0.48) | — | |
| SCHEMBL13663 | 0.75 | — | — | |
| SCHEMBL505542 | 0.75 | — | — | |
| SCHEMBL29388695 | 0.75 | — | — | |
| SCHEMBL29394596 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL1795985 | 0.72 | KDM4E (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573095-A1 | PYRIDOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024040131-A1 | PYRIDOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2024-02-22 | — | — | WO | disclosed |
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022211498-A1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | 주식회사 엘지화학 | 2022-10-06 | — | — | WO | disclosed |