Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938707 | 0.80 | TDP1 (0.47) | TDP1TSHRMAPTMAOBRAB9A | |
| SCHEMBL2194744 | 0.80 | TDP1 (0.54) | TDP1TSHRMAPTMAOBRAB9A | |
| SCHEMBL12660720 | 0.79 | TDP1 (0.58) | TDP1TSHRMAPTMAOBRAB9A | |
| SCHEMBL10596571 | 0.79 | TDP1 (0.46) | TDP1TSHRMAPTMAOBRAB9A | |
| SCHEMBL4622599 | 0.79 | CYP3A4 (0.56) | TSHRMAPTMAOBALDH1A1CYP3A4 | |
| SCHEMBL10942315 | 0.78 | TDP1 (0.45) | TDP1TSHRMAPTRAB9AGAA | |
| SCHEMBL11311338 | 0.72 | TDP1 (0.48) | TDP1TSHRMAPTMAOBRAB9A | |
| SCHEMBL11316263 | 0.72 | TDP1 (0.48) | TDP1TSHRMAPTMAOBRAB9A | |
| SCHEMBL11317761 | 0.70 | TDP1 (0.43) | TDP1TSHRMAPTMAOBRAB9A | |
| SCHEMBL28446580 | 0.69 | TDP1 (0.44) | TDP1TSHRMAPTMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499149-A | ADHESION; HEAT RESISTANCE; PROTECTIVE COATINGS; SEMICONDUCTORS; POLYIMIDES | M&T CHEMICALS INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4480009-A | POLYIMIDE, POLYAMIDEIMIDE, OR POLY-HALF-AMIDE | M&T CHEMICALS INC. (US) | 1984-10-30 | — | — | US | disclosed |
| US-4395527-A | POLYIMIDES FROM AMINOPOLYSILOXANES | M & T CHEMICALS INC. (US) | 1983-07-26 | — | — | US | disclosed |
| EP-0054426-A2 | Improvements in or relating to siloxanes | M & T CHEMICALS, INC. (US) | 1982-06-23 | — | — | EP | disclosed |