Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217358 | 0.83 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| Adrafinil SCHEMBL4291451 | 0.83 | HDAC8 (0.47) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL19664525 | 0.83 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL24871094 | 0.81 | CNR2 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL29131279 | 0.81 | CNR2 (0.41) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL29131264 | 0.79 | ALDH1A1 (0.47) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL10937730 | 0.79 | CNR2 (0.47) | HDAC6HDAC8HDAC4HDAC7HDAC5 | |
| SCHEMBL9212520 | 0.78 | EPHX1 (0.47) | CNR2KDM4EALDH1A1HTT | |
| SCHEMBL2615349 | 0.75 | ALDH1A1 (0.43) | CNR2KDM4EALDH1A1HTT | |
| SCHEMBL2615348 | 0.75 | ALDH1A1 (0.43) | CNR2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097547-B1 | HALOGENOBENZHYDRYLSULFINYLACETOHYDROXAMIC ACIDS, PREPARATION AND THERAPEUTICAL USE | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1985-08-28 | — | — | EP | claimed |
| US-4489095-A | PSYCHOTONIC AND ANTIAGGRESSION AGENTS | LABORATOIRE L. LAFON (FR) | 1984-12-18 | — | — | US | disclosed |