SCHEMBL29131279

SCHEMBL29131279

O=C(O)C[S@+]([O-])C(c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.41
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
FFAR1 O14842 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
PTPN1 P18031 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
HTT P42858 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24871094 1.00 CNR2 (0.41) CNR2KDM4EALDH1A1FFAR1HDAC3
SCHEMBL9217358 0.84 HDAC3 (0.41) CNR2KDM4EALDH1A1HDAC3HDAC4
SCHEMBL19664525 0.84 HDAC3 (0.41) CNR2KDM4EALDH1A1HDAC3HDAC4
SCHEMBL3912386 0.83 CES2 (0.41) CNR2
SCHEMBL900143 0.83 CES2 (0.41) CNR2
SCHEMBL4057742 0.83 CES2 (0.41) CNR2
SCHEMBL9212520 0.82 EPHX1 (0.47) CNR2KDM4EALDH1A1HTT
SCHEMBL2615349 0.82 ALDH1A1 (0.43) CNR2KDM4EALDH1A1HTT
SCHEMBL2615348 0.82 ALDH1A1 (0.43) CNR2KDM4EALDH1A1HTT
SCHEMBL10938696 0.81 HDAC3 (0.46) CNR2KDM4EALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117303992-A Preparation method of polyfunctional group substituted chiral sulfoxide compound 厦门大学 2023-12-29 CN disclosed