SCHEMBL9217358

SCHEMBL9217358

NC(=O)C[S+]([O-])C(c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
EPHX1 P07099 1/20 0.38
CNR2 P34972 1/20 0.36
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36
ALDH1A1 P00352 2/20 0.35
KCNN4 O15554 1/20 0.35
PTPN1 P18031 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19664525 1.00 HDAC3 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9212520 0.94 EPHX1 (0.47) EPHX1CNR2ALDH1A1KCNN4KDM4E
SCHEMBL24871094 0.84 CNR2 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL29131279 0.84 CNR2 (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL10938696 0.83 HDAC3 (0.46) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL19676420 0.83 HDAC3 (0.35) HDAC3HDAC4HDAC1HDAC7HDAC2
(S)-Modafinil SCHEMBL1403524 0.82 CYP2D6 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
Armodafinil SCHEMBL34489 0.82 CYP2D6 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
Modafinil SCHEMBL3238686 0.82 CYP2D6 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
Modafinil SCHEMBL34488 0.82 CYP2D6 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240342119-A1 COMPOSITION FOR TREATING HYPERTROPHIC SCARS AND KELOIDS COMPRISING BENZHYDRYL THIOACETAMIDE COMPOUND AS ACTIVE INGREDIENT CELLIONBIOMED INC. (KR) 2024-10-17 US claimed
EP-4368177-A1 COMPOSITION FOR TREATING HYPERTROPHIC SCARS AND KELOIDS COMPRISING BENZHYDRYL THIOACETAMIDE COMPOUND AS ACTIVE INGREDIENT Cellionbiomed Inc. (KR) 2024-05-15 EP claimed
WO-2023014003-A1 COMPOSITION FOR TREATING HYPERTROPHIC SCARS AND KELOIDS COMPRISING BENZHYDRYL THIOACETAMIDE COMPOUND AS ACTIVE INGREDIENT 셀라이온바이오메드 주식회사 2023-02-09 WO claimed
EP-3851099-A1 COMPOSITION FOR TREATING FIBROTIC DISEASES, COMPRISING BENZHYDRYL THIOACETAMIDE COMPOUND AS ACTIVE INGREDIENT Cellionbiomed Inc. (KR) 2021-07-21 EP claimed
CN-113038942-A Composition for treating fibrotic diseases containing benzhydrylthioacetamide (Benzhydryl ttoacetamide) compound as active ingredient 细胞离子生物医学株式会社 2021-06-25 CN claimed
WO-1995001171-A1 USE OF ACETAMIDE DERIVATIVES FOR MODIFYING FEEDING BEHAVIOUR LABORATOIRE L. LAFON (FR) 1995-01-12 WO claimed
EP-0097071-B1 BENZHYDRYL SULFINYLACETAMIDE DERIVATIVES AND THEIR THERAPEUTICAL USE LABORATOIRE L. LAFON Société anonyme dite: (FR) 1985-08-28 EP claimed
EP-0097071-A1 Benzhydryl sulfinylacetamide derivatives and their therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1983-12-28 EP claimed
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 US disclosed
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles Triastek, Inc. (CN) 2025-06-10 US disclosed
CN-119735613-A Crystalline forms of 5-chloro-N4- [2- (dimethylphosphoryl) phenyl ] -N2- { 2-methoxy-4- [4- (4-methylpiperazin-1-yl) piperidin-1-yl ] phenyl } pyrimidine-2, 4-diamine 武田药品工业株式会社 2025-04-01 CN disclosed
US-20250085301-A1 DATE RAPE DRUG DETECTION DEVICE AND METHOD OF USING SAME EHRLICH ELAN (IL) 2025-03-13 US disclosed
US-20250076321-A1 DATE RAPE DRUG DETECTION DEVICE AND METHOD OF USING SAME EHRLICH ELAN (IL) 2025-03-06 US disclosed
US-20250076324-A1 DATE RAPE DRUG DETECTION DEVICE AND METHOD OF USING SAME EHRLICH ELAN (IL) 2025-03-06 US disclosed
US-20130295196-A1 LAUFLUMIDE AND THE ENANTIOMERS THEREOF, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (FR) 2013-11-07 US disclosed
WO-2012098235-A1 LAUFLUMIDE AND THE ENANTIOMERS THEREOF, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) 2012-07-26 WO disclosed
WO-2012098235-A1 LAUFLUMIDE AND THE ENANTIOMERS THEREOF, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) 2012-07-26 WO disclosed
WO-1995001171-A1 USE OF ACETAMIDE DERIVATIVES FOR MODIFYING FEEDING BEHAVIOUR LABORATOIRE L. LAFON (FR) 1995-01-12 WO disclosed
EP-0097071-B1 BENZHYDRYL SULFINYLACETAMIDE DERIVATIVES AND THEIR THERAPEUTICAL USE LABORATOIRE L. LAFON Société anonyme dite: (FR) 1985-08-28 EP disclosed
EP-0097071-A1 Benzhydryl sulfinylacetamide derivatives and their therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1983-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles CYP2D6, CYP3A5, CYP3A7 HDAC3 1315/4885HDAC4 1590/4885HDAC1 935/4885
US-20130295196-A1 LAUFLUMIDE AND THE ENANTIOMERS THEREOF, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF HCRTR2, HNMT, CYP2U1 HDAC3 1015/4885HDAC4 648/4885HDAC1 987/4885
US-20240342119-A1 COMPOSITION FOR TREATING HYPERTROPHIC SCARS AND KELOIDS COMPRISING BENZHYDRYL THIOACETAMIDE COMPOUND AS ACTIVE INGREDIENT TRPV5, COL2A1, FIBP HDAC3 853/4885HDAC4 545/4885HDAC1 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.