Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.38 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.38 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448617 | 0.78 | ALDH1A1 (0.53) | CA2CA9CA12ALDH1A1HSD17B10 | |
| SCHEMBL10935481 | 0.78 | ALDH1A1 (0.60) | GLO1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11216562 | 0.78 | ALDH1A1 (0.60) | GLO1CA2CA9CA12ALDH1A1 | |
| SCHEMBL30249676 | 0.74 | CA1 (0.42) | CA2CA9CA1STSGAA | |
| SCHEMBL9172206 | 0.73 | MEN1 (0.55) | GLO1CA2CA9CA12ALDH1A1 | |
| SCHEMBL9172195 | 0.73 | MEN1 (0.55) | GLO1CA2CA9CA12ALDH1A1 | |
| SCHEMBL10707831 | 0.73 | MEN1 (0.55) | GLO1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11219752 | 0.73 | HSD17B10 (0.66) | GLO1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11578943 | 0.73 | HSD17B10 (0.66) | GLO1CA2CA9CA12ALDH1A1 | |
| SCHEMBL1243178 | 0.71 | STS (0.51) | CA2CA9CA12ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079858-B1 | AZO DYESTUFFS, METAL COMPLEXES THEREOF, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1985-12-27 | — | — | EP | disclosed |
| EP-0079858-A1 | Azo dyestuffs, metal complexes thereof, their preparation and use | CIBA-GEIGY AG (CH) | 1983-05-25 | — | — | EP | disclosed |