Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.56 |
| ▸ | PGR | P06401 | 6/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 8/20 | 0.55 |
| ▸ | AR | P10275 | 5/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | SNCA | P37840 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041227 | 0.93 | PGR (0.64) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| SCHEMBL18218187 | 0.93 | PGR (0.64) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| SCHEMBL14256378 | 0.93 | PGR (0.64) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| SCHEMBL14256416 | 0.93 | PGR (0.64) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| SCHEMBL18220867 | 0.87 | SHBG (0.54) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| Spriolactone SCHEMBL14285054 | 0.80 | SHBG (0.67) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| Spriolactone SCHEMBL20459223 | 0.80 | SHBG (0.67) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| Spriolactone SCHEMBL18218188 | 0.80 | SHBG (0.67) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| Spriolactone SCHEMBL10786113 | 0.80 | SHBG (0.67) | SHBGPGRNR3C1ALDH1A1HTR2B | |
| Spriolactone SCHEMBL8259555 | 0.80 | SHBG (0.67) | SHBGPGRNR3C1ALDH1A1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507238-A | Process for the preparation of 3-(Δ4 -3-ketosteroid-17α-yl)propionic acid lactones | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-26 | — | — | US | disclosed |