Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.64 |
| ▸ | AR | P10275 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | SHBG | P04278 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256416 | 1.00 | PGR (0.64) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL18218187 | 1.00 | PGR (0.64) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL14256378 | 1.00 | PGR (0.64) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL10939751 | 0.93 | SHBG (0.56) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL18220867 | 0.86 | SHBG (0.54) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL13936414 | 0.84 | CYP19A1 (0.54) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL13103488 | 0.84 | PGR (0.72) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL14668726 | 0.84 | PGR (0.72) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL12568120 | 0.83 | PGR (0.65) | PGRARLMNANR3C1HTR2B | |
| SCHEMBL16852314 | 0.83 | PGR (0.65) | PGRARLMNANR3C1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061418-B1 | 7-ALPHA-ALKOXYCARBONYL-15-BETA-16-BETA-METHYLENE-4 ANDROSTENE, PROCESS FOR THEIR PREPARATION AND THEIR UTILIZATION AS PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-08-21 | — | — | EP | disclosed |
| US-4450107-A | 7α-Alkoxycarbonyl-15β,16β-methylene-4-androstenes, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |
| EP-0061418-A1 | 7-Alpha-alkoxycarbonyl-15-beta-16-beta-methylene-4 androstene, process for their preparation and their utilization as pharmaceutical preparations | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-09-29 | — | — | EP | disclosed |