SCHEMBL3489282

SCHEMBL3489282

N[C@@H](CC(=O)OC(=O)[C@@H]1CCCN1)C(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
PRCP P42785 1/20 0.32
DPP7 Q9UHL4 2/20 0.32
DPP4 P27487 4/20 0.31
DPP8 Q6V1X1 2/20 0.31
DPP9 Q86TI2 2/20 0.31
TLR2 O60603 2/20 0.30
ELANE P08246 1/20 0.30
GLI1 P08151 1/20 0.30
FAP Q12884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2537702 0.88 NOS2 (0.39) NOS2NOS3NOS1PRCPDPP7
SCHEMBL7536202 0.88 NOS2 (0.35) NOS2NOS3NOS1PRCPDPP7
SCHEMBL1680032 0.88 GRIK1 (0.37) NOS2NOS3NOS1PRCPDPP7
SCHEMBL2201568 0.86 NOS2 (0.33) NOS2NOS3NOS1PRCPDPP7
SCHEMBL285831 0.85 NOS2 (0.37) NOS2NOS3NOS1PRCPDPP7
SCHEMBL756555 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL11858950 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL1537227 0.84 SLC7A5 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL51271 0.84 NOS2 (0.36) NOS2NOS3NOS1PRCPDPP7
SCHEMBL10940484 0.83 CTSC (0.45) DPP7DPP4DPP8DPP9ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023099452-A1 DIALYSIS FLUID COMPRISING KETONE BODIES FOR THE TREATMENT OF CANCER GAMBRO LUNDIA AB (SE) 2023-06-08 WO claimed
WO-2023099436-A1 NEW DIALYSIS FLUID GAMBRO LUNDIA AB (SE) 2023-06-08 WO claimed
CN-105327081-A Traditional Chinese medicine composition for preventing and curing emphysema and preparation method LI TAO 2016-02-17 CN disclosed
CN-105288193-A Yin nourishing and heat clearing preparation for treating pulmonary heart diseases, and preparation method thereof LI TAO 2016-02-03 CN disclosed
CN-105233033-A Preparation for treating nervous tinnitus and preparation method of preparation LI YOUHUA 2016-01-13 CN disclosed
US-20130338069-A1 Preparation of a Therapeutic Composition OHR PHARMACEUTICAL INC. (US) 2013-12-19 US disclosed
CN-102822413-A Process of treatment of fibers and/or textile materials LIPOTEC SA 2012-12-12 CN disclosed
US-20120271032-A1 Preparation of a Therapeutic Composition OHR PHARMACEUTICAL INC. (US) 2012-10-25 US disclosed
US-8084239-B2 Preparation of a therapeutic composition Ohr Pharmaceuticals, Inc (US) 2011-12-27 US disclosed
US-20100080820-A1 Preparation of a Therapeutic Composition BBM HOLDINGS, INC. (US) 2010-04-01 US disclosed
US-7524661-B2 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORPORATION (US) 2009-04-28 US disclosed
US-20060177514-A1 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. 2006-08-10 US disclosed
US-7074767-B2 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. (US) 2006-07-11 US disclosed
US-6921542-B2 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. (US) 2005-07-26 US disclosed
US-20030158107-A1 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. 2003-08-21 US disclosed
US-20030134782-A1 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. 2003-07-17 US disclosed
US-6528098-B2 Viricides ADVANCED VIRAL RESEARCH CORP. 2003-03-04 US disclosed
US-20020004579-A1 Preparation of a therapeutic composition ADVANCED VIRAL RESEARCH CORP. 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158107-A1 Preparation of a therapeutic composition VIP, FCGR3B, FCGRT NOS2 3235/4885NOS3 3243/4885NOS1 3649/4885
US-20020004579-A1 Preparation of a therapeutic composition VIP, FCGR3B, FCGRT NOS2 3235/4885NOS3 3243/4885NOS1 3649/4885
US-20030134782-A1 Preparation of a therapeutic composition VIP, FCGR3B, FCGRT NOS2 3235/4885NOS3 3243/4885NOS1 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.