Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940483 | 1.00 | OGG1 (0.40) | OGG1KMT2AMEN1CYP1A2ATM | |
| SCHEMBL10938163 | 0.87 | TRPV1 (0.33) | KMT2AMEN1POLBPRSS1CTSG | |
| SCHEMBL10934466 | 0.87 | MAPK1 (0.42) | KMT2AMEN1CYP1A2L3MBTL1LMNA | |
| SCHEMBL10938164 | 0.87 | TRPV1 (0.33) | KMT2AMEN1POLBPRSS1CTSG | |
| SCHEMBL10937589 | 0.87 | CTSL (0.44) | KMT2AATMCTSSCTSLLMNA | |
| SCHEMBL10934472 | 0.87 | MAPK1 (0.42) | KMT2AMEN1CYP1A2L3MBTL1LMNA | |
| SCHEMBL10937584 | 0.87 | CTSL (0.44) | KMT2AATMCTSSCTSLLMNA | |
| SCHEMBL10936648 | 0.87 | OGG1 (0.41) | OGG1KMT2AMEN1CYP1A2CTSS | |
| SCHEMBL10936654 | 0.87 | OGG1 (0.41) | OGG1KMT2AMEN1CYP1A2CTSS | |
| SCHEMBL10938064 | 0.84 | CA12 (0.43) | L3MBTL1POLBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545942-A | IMMUNOREGULATORS; ANTITUMOR AGENTS | SANKYO COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | claimed |