Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936654 | 1.00 | OGG1 (0.41) | OGG1FPR2CTSSCTSBCTSL | |
| SCHEMBL10940488 | 0.87 | OGG1 (0.40) | OGG1CTSSCTSBCTSLHDAC3 | |
| SCHEMBL10940483 | 0.87 | OGG1 (0.40) | OGG1CTSSCTSBCTSLHDAC3 | |
| SCHEMBL10936635 | 0.86 | CTSL (0.48) | CTSSCTSBCTSLCTSKALDH1A1 | |
| SCHEMBL10940237 | 0.86 | ALDH1A1 (0.43) | CTSBPOLBALDH1A1KDM4EMAPT | |
| SCHEMBL10940243 | 0.86 | ALDH1A1 (0.43) | CTSBPOLBALDH1A1KDM4EMAPT | |
| SCHEMBL10939776 | 0.86 | FOLH1 (0.37) | CTSLPOLB | |
| SCHEMBL10936639 | 0.86 | CTSL (0.48) | CTSSCTSBCTSLCTSKALDH1A1 | |
| SCHEMBL10939773 | 0.86 | FOLH1 (0.37) | CTSLPOLB | |
| SCHEMBL10935401 | 0.77 | CTSV (0.47) | CTSSCTSBCTSLCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545942-A | IMMUNOREGULATORS; ANTITUMOR AGENTS | SANKYO COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | claimed |