Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057475 | 0.79 | ALDH1A1 (0.47) | CYP1A2KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL11895859 | 0.78 | CYP1A2 (0.50) | CYP1A2GAAPOLBALDH1A1KDM4E | |
| SCHEMBL30336104 | 0.76 | CYP1A2 (0.54) | CYP1A2KMT2AGAAPTPN22ALDH1A1 | |
| SCHEMBL599137 | 0.76 | CYP1A2 (0.54) | CYP1A2KMT2AGAAPTPN22ALDH1A1 | |
| SCHEMBL466616 | 0.76 | HNF4A (0.46) | ALDH1A1HPGDTDP1HSD17B10MAPK1 | |
| SCHEMBL30208655 | 0.75 | MAPT (0.44) | CYP1A2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10934703 | 0.75 | HDAC4 (0.54) | CYP1A2CNR2ACMSDCYP2C19 | |
| Phenol SCHEMBL28500216 | 0.73 | CYP1A2 (0.46) | CYP1A2KMT2APTPN22ALDH1A1KDM4E | |
| SCHEMBL28164845 | 0.73 | HPRT1 (0.52) | CYP1A2KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL4443508 | 0.71 | PTPN22 (0.56) | PPARGCYP1A2KMT2AGAAPTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4495320-A | 3,6-Di-t-butyl-2-naphthyl catechol phosphite and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-01-22 | — | — | US | disclosed |