Sugi Predict

Sugi Predict / Compounds / SCHEMBL4443508

SCHEMBL4443508

SCHEMBL4443508

Oc1c(-c2cccc3ccccc23)ccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN22 Q9Y2R2 1/20 0.56
▸ CYP1A2 P05177 2/20 0.48
▸ LDHA P00338 1/20 0.47
▸ HSD17B10 Q99714 3/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ CYP2A6 P11509 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ CASP3 P42574 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401627 0.91 PTPN22 (0.65) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL374807 0.91 PTPN22 (0.65) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL599137 0.89 CYP1A2 (0.54) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL30336104 0.89 CYP1A2 (0.54) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL1840828 0.89 PTPN22 (0.62) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL5155985 0.89 PTPN22 (0.62) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL9060860 0.89 PTPN22 (0.62) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL27035048 0.87 PTPN22 (0.47) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL460618 0.85 PTPN22 (0.59) PTPN22CYP1A2LDHAHSD17B10ALDH1A1
SCHEMBL6634384 0.84 PTPN22 (0.58) PTPN22CYP1A2LDHAHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524896-B2 Hydroxypivalyl hydroxypivalate ester plasticizer composition and method of preparing the same LG CHEM, LTD. (KR) 2009-04-28 — — US claimed
US-20070015933-A1 Hydroxypivalyl hydroxypivalate ester plasticizer composition and method of preparing the same LG CHEM, LTD. (KR) 2007-01-18 — — US claimed
US-20250163228-A1 POLYESTER RESIN, RESIN COMPOSITION, CURED PRODUCT THEREOF, AND USE THEREOF AJINOMOTO CO., INC. (JP) 2025-05-22 — — US disclosed
CN-119585340-A Polyester resin, resin composition, cured product thereof, and use thereof 味之素株式会社 2025-03-07 — — CN disclosed
WO-2024018949-A1 POLYESTER RESIN, RESIN COMPOSITION, CURED PRODUCT THEREOF, AND USE THEREOF 味の素株式会社 2024-01-25 — — WO disclosed
US-10005780-B2 Production method of imidazole derivatives TAKEDA PHARMACEUTICAL COMPANY (JP) 2018-06-26 — — US disclosed
US-20160244454-A1 PRODUCTION METHOD OF IMIDAZOLE DERIVATIVES TAKEDA PHARMACEUTICALS CO (JP) 2016-08-25 — — US disclosed
US-9278938-B2 Production method of imidazole derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-03-08 — — US disclosed
EP-2721010-B1 PRODUCTION METHOD OF IMIDAZOLE DERIVATIVES TAKEDA PHARMACEUTICAL (JP) 2015-09-09 — — EP disclosed
EP-2721010-A1 PRODUCTION METHOD OF IMIDAZOLE DERIVATIVES Takeda Pharmaceutical Company Limited (JP) 2014-04-23 — — EP disclosed
US-20140100373-A1 PRODUCTION METHOD OF IMIDAZOLE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-04-10 — — US disclosed
US-5342759-A Signal generating system having specific binding pairs SYVA COMPANY (US) 1994-08-30 — — US disclosed
US-5156953-A Binding catalyst with second surface in a predeterminded ratio to the amount bound to the first surface, whereby the ratio of the signals defines the amount of analyte SYNTEX (U.S.A.) INC. (US) 1992-10-20 — — US disclosed
US-4849338-A Simultaneous calibration heterogeneous immunoassay SYNTEX (U.S.A.) INC. (US) 1989-07-18 — — US disclosed
US-4843000-A BINDING OF LABELED REAGENT TO ONE SEGMENT; DETERMINATION BY COMPARISON OF SIGNAL LEVEL SYNTEX (U.S.A.) INC. (US) 1989-06-27 — — US disclosed
US-4540659-A Simultaneous calibration heterogeneous immunoassay SYVA COMPANY (US) 1985-09-10 — — US disclosed
US-4533629-A Simultaneous calibration heterogeneous immunoassay SYVA COMPANY (US) 1985-08-06 — — US disclosed
US-4391904-A Test strip kits in immunoassays and compositions therein SYVA COMPANY (US) 1983-07-05 — — US disclosed
US-4366241-A Concentrating zone method in heterogeneous immunoassays SYVA COMPANY (US) 1982-12-28 — — US disclosed
US-4299916-A COLORIMETRIC ANALYSIS OF ANALYTES SYVA COMPANY (US) 1981-11-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244454-A1 PRODUCTION METHOD OF IMIDAZOLE DERIVATIVES GRIK4, PPIP5K2, IP6K2 PTPN22 4734/4885CYP1A2 387/4885LDHA 1383/4885
US-10005780-B2 Production method of imidazole derivatives GRIK4, PPIP5K2, IP6K2 PTPN22 4734/4885CYP1A2 387/4885LDHA 1383/4885
US-20140100373-A1 PRODUCTION METHOD OF IMIDAZOLE DERIVATIVES GRIK4, PPIP5K2, IP6K2 PTPN22 4734/4885CYP1A2 387/4885LDHA 1383/4885
US-20070015933-A1 Hydroxypivalyl hydroxypivalate ester plasticizer composition and method of preparing the same COL14A1, HPD, HSPA4L PTPN22 2476/4885CYP1A2 1323/4885LDHA 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.