Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | PKM | P14618 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | RAB27A | P51159 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179945 | 0.86 | LMNA (0.57) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL4179940 | 0.86 | LMNA (0.57) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL10944619 | 0.81 | MAPT (0.61) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL11376928 | 0.79 | SMN1; SMN2 (0.59) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL11376924 | 0.79 | SMN1; SMN2 (0.59) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL10945521 | 0.77 | MAPT (0.57) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL10945514 | 0.77 | MAPT (0.57) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL8781969 | 0.77 | MAPT (0.80) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL8781966 | 0.77 | MAPT (0.80) | MAPTRAB9APKMSMN1; SMN2HTT | |
| SCHEMBL10383575 | 0.76 | RAB9A (0.57) | MAPTRAB9APKMSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079006-B1 | AZOLYL ALKENONES AND OLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULATORS AND FUNGICIDES | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
| US-4500537-A | MICROBIOCIDES, PLANT SAFENING AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0040368-B1 | TRIAZOLYL VINYL KETONES AND CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1983-09-28 | — | — | EP | disclosed |
| EP-0079006-A1 | Azolyl alkenones and ols, process for their preparation and their use as plant growth regulators and fungicides | BAYER AG (DE) | 1983-05-18 | — | — | EP | disclosed |
| US-4380628-A | REACTING THE KETO-ENAMINE-SUBSTITUTED IMIDAZOLE OR 1,2,4-TRIAZOLE DERIVATIVE WITH A GINR ARD REAGENT; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-19 | — | — | US | disclosed |
| EP-0032239-B1 | METHOD FOR PREPARING AZOLYL-VINYL-KETONES | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| EP-0040368-A1 | Triazolyl vinyl ketones and carbinols, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |
| EP-0032239-A1 | Method for preparing azolyl-vinyl-ketones | BAYER AG (DE) | 1981-07-22 | — | — | EP | disclosed |